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Strategies to Manage Hepatitis C Virus Infection Disease Burden - Volume 3 Publisher Pubmed



Alfaleh FZ1 ; Nugrahini N2 ; Maticic M3 ; Tolmane I4, 5 ; Alzaabi M6 ; Hajarizadeh B7, 8 ; Valantinas J9 ; Kim DY10 ; Hunyady B11, 12 ; Abaalkhail F13 ; Abbas Z14 ; Abdou A15 ; Abourached A16 ; Al Braiki F17 Show All Authors
Authors
  1. Alfaleh FZ1
  2. Nugrahini N2
  3. Maticic M3
  4. Tolmane I4, 5
  5. Alzaabi M6
  6. Hajarizadeh B7, 8
  7. Valantinas J9
  8. Kim DY10
  9. Hunyady B11, 12
  10. Abaalkhail F13
  11. Abbas Z14
  12. Abdou A15
  13. Abourached A16
  14. Al Braiki F17
  15. Al Hosani F18
  16. Al Jaberi K19
  17. Al Khatry M20
  18. Al Mulla MA18
  19. Al Quraishi H21
  20. Al Rifai A22
  21. Al Serkal Y23
  22. Alam A24
  23. Alashgar HI25
  24. Alavian SM26, 27
  25. Alawadhi S15
  26. Aldabal L28
  27. Aldins P29
  28. Alghamdi AS30
  29. Alhakeem R31
  30. Aljumah AA32
  31. Almessabi A17
  32. Alqutub AN30
  33. Alswat KA33
  34. Altraif I32
  35. Andrea N34
  36. Assiri AM31
  37. Babatin MA30
  38. Baqir A35
  39. Barakat MT36
  40. Bergmann OM37
  41. Bizri AR38
  42. Chaudhry A39
  43. Choi MS40
  44. Diab T41
  45. Djauzi S42
  46. El Hassan ES15
  47. El Khoury S43
  48. Estes C44
  49. Fakhry S45
  50. Farooqi JI46, 47
  51. Fridjonsdottir H48, 58, 59
  52. Gani RA42
  53. Ghafoor Khan A49
  54. Gheorghe L50
  55. Goldis A51
  56. Gottfredsson M52
  57. Gregorcic S3
  58. Gunter J44
  59. Hamid S53
  60. Han KH10
  61. Hasan I42
  62. Hashim A54
  63. Horvath G55
  64. Husni R56
  65. Jafri W57
  66. Jeruma A4, 5
  67. Jonasson JG48, 58, 59
  68. Karlsdottir B60
  69. Kim YS61
  70. Koutoubi Z62
  71. Lesmana LA42, 63
  72. Liakina V9, 64
  73. Lim YS65
  74. Love A52, 66
  75. Maimets M67
  76. Makara M68
  77. Malekzadeh R69
  78. Memon MS70
  79. Merat S69
  80. Mokhbat JE71
  81. Mourad FH72
  82. Muljono DH73, 74
  83. Nawaz A75
  84. Olafsson S37
  85. Priohutomo S76
  86. Qureshi H77
  87. Rassam P43
  88. Razavi H44
  89. Razavishearer D44
  90. Razavishearer K44
  91. Rozentale B4
  92. Sadik M70
  93. Saeed K78
  94. Salamat A79
  95. Salupere R67
  96. Sanai FM1
  97. Sanityoso Sulaiman A42
  98. Sayegh RA80
  99. Schmelzer JD44
  100. Sharara AI72
  101. Sibley A44
  102. Siddiq M81, 82, 83
  103. Siddiqui AM83
  104. Sigmundsdottir G84, 85
  105. Sigurdardottir B60
  106. Speiciene D9
  107. Sulaiman A42, 86
  108. Sultan MA86
  109. Taha M87
  110. Tanaka J88
  111. Tarifi H89
  112. Tayyab G90, 91
  113. Ud Din M92
  114. Umar M93, 94
  115. Videcnikzorman J3
  116. Yaghi C80, 81
  117. Yunihastuti E95
  118. Yusuf MA96
  119. Zuberi BF97
  120. Blach S44
Show Affiliations
Authors Affiliations
  1. 1. Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia
  2. 2. Sub-Direct. for Gastrointestinal Infection, Diarrheal Diseases, and Hepatitis, Direct. of Direct Transmitted Disease Control, Disease Control and Environmental Health, Ministry of Health, Jakarta, Indonesia
  3. 3. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre, Ljubljana, Slovenia
  4. 4. Department of Hepatology, Infectology Center of Latvia, Riga, Latvia
  5. 5. Department of Infectology and Dermatology, Riga Stradins University, Riga, Latvia
  6. 6. Zayed Military Hospital, Abu Dhabi, United Arab Emirates
  7. 7. Kirby Institute, University of New South Wales Australia, Sydney, Australia
  8. 8. Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia
  9. 9. Centre of Hepatology, Gastroenterology, and Dietetics, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
  10. 10. Department of Internal Medicine, Yonsei University, College of Medicine, Seoul, South Korea
  11. 11. Department of Gastroenterology, Somogy County Kaposi, Mor Teaching Hospital, Kaposvar, Hungary
  12. 12. First Department of Medicine, University of Pecs, Pecs, Hungary
  13. 13. Department of Liver and Small Bowel Transplantation, King Faisal Specialist Hospital and, Research Center, Alfaisal University, Riyadh, Saudi Arabia
  14. 14. Ziauddin University, Karachi, Pakistan
  15. 15. Rashid Hospital Dubai Health Authority, Dubai, United Arab Emirates
  16. 16. National Hepatitis Program, Ministry of Public Health, Beirut, Lebanon
  17. 17. Abu Dhabi Health Services Company, Abu Dhabi, United Arab Emirates
  18. 18. Communicable Diseases Department, Health Authority Abu Dhabi, Abu Dhabi, United Arab Emirates
  19. 19. Health Regulation Division, Health Authority Abu Dhabi, Abu Dhabi, United Arab Emirates
  20. 20. Ras Al Khaimah Hospital, Ras Al Khaimah, United Arab Emirates
  21. 21. Dubai Health Authority, Dubai, United Arab Emirates
  22. 22. Mafraq Hospital, Abu Dhabi, United Arab Emirates
  23. 23. Hospitals Sector, Ministry of Health, Al-Ain, United Arab Emirates
  24. 24. Shaikh Zayed Hospital, Lahore, Pakistan
  25. 25. Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
  26. 26. Baqiatallah Research Center for Gastroenterology and Liver Diseases, Baqiatallah University of Medical Sciences, Tehran, Iran
  27. 27. Middle East Liver Diseases Centre, Tehran, Iran
  28. 28. Department of Pulmonary Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates
  29. 29. Infection Control Department, Pauls Stradins Clinical, University Hospital, Riga, Latvia
  30. 30. Gastroenterology and Hepatology Unit, Medical Specialties Department, King Fahad Hospital, Riyadh, Saudi Arabia
  31. 31. Department of Preventive Medicine, Ministry of Health, Riyadh, Saudi Arabia
  32. 32. King Abdulaziz Medical City and King Saud Bin Abdulaziz, University for Health Sciences, Riyadh, Saudi Arabia
  33. 33. Department of Medicine, King Saud University Liver Disease Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
  34. 34. Daman National Health Insurance Company, Abu Dhabi, United Arab Emirates
  35. 35. Seyal Medical Centre, Multan, Pakistan
  36. 36. Health Authority Abu Dhabi, Abu Dhabi, United Arab Emirates
  37. 37. Division of Gastroenterology and Hepatology, Landspitali, National University, Hospital of Iceland, Reykjavik, Iceland
  38. 38. Faculty of Medicine, Division of Infectious Diseases, American University of Beirut Medical Center, Beirut, Lebanon
  39. 39. Gujranwala Liver Foundation, Siddiq Sadiq Hospital, Gujranwala, Pakistan
  40. 40. Department of Medicine, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, South Korea
  41. 41. Al Ain Hospital, Al Ain, United Arab Emirates
  42. 42. Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  43. 43. Gastroenterology Department, Saint George Hospital, University of Balamand, El-Koura, Lebanon
  44. 44. Center for Disease Analysis (CDA), Louisville, CO, United States
  45. 45. Abu Dhabi Police, Abu Dhabi, United Arab Emirates
  46. 46. Postgraduate Medical Institute, Khyber Medical University, Peshawar, Pakistan
  47. 47. Government Lady Reading Hospital, Peshawar, Pakistan
  48. 48. Landspitali - the National University Hospital of Iceland, Reykjavik, Iceland
  49. 49. Department of Gastroenterology and Hepatology, Lady Reading Hospital, Peshawar, Pakistan
  50. 50. Center of Gastroenterology and Hepatology, Fundeni Clinical Institute, Bucharest, Romania
  51. 51. Clinic of Gastroenterology, University of Medicine 'Victor Babes', Timisoara, Romania
  52. 52. Faculty of Medicine, School of Health Sciences, Landspitali - the National University, Hospital of Iceland, Reykjavik, Iceland
  53. 53. Aga Khan University, Karachi, Pakistan
  54. 54. Liver Transplantation, King Faisal Specialist Hospital, Research Centre, Riyadh, Saudi Arabia
  55. 55. Hepatology Center of Buda, Budapest, Hungary
  56. 56. Lebanese American University Medical Center, Rizk Hospital, Beirut, Lebanon
  57. 57. Aga Khan University, Karachie, Pakistan
  58. 58. Icelandic Cancer Registry, Reykjavik, Iceland
  59. 59. Faculty of Medicine, Landspitali - the National University, Hospital of Iceland, Reykjavik, Iceland
  60. 60. Division of Infectious Disease, Landspitali - the National University, Hospital of Iceland, Reykjavik, Iceland
  61. 61. Department of Internal Medicine, Soon Chun Hyang University, Bucheon Hospital, Bucheon, South Korea
  62. 62. Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates
  63. 63. Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia
  64. 64. Department of Biomechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania
  65. 65. Department of Gastroenterology, Asan Medical Center, University of Ulsan, College of Medicine, Songpa-gu, Seoul, South Korea
  66. 66. Department of Virology, Landspitali - the National University, Hospital of Iceland, Reykjavik, Iceland
  67. 67. Tartu University Hospital, University of Tartu, Tartu, Estonia
  68. 68. Central Outpatient Clinic, Saint Laszlo Hospital, Budapest, Hungary
  69. 69. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  70. 70. Asian Institute of Medical Science (AIMS), Hyderabad-Sindh, Pakistan
  71. 71. Division of Infectious Diseases, Division of Clinical Microbiology, Lebanese American University Medical Center, Rizk Hospital, Beirut, Lebanon
  72. 72. Division of Gastroenterology, American University of Beirut Medical Center, Beirut, Lebanon
  73. 73. Eijkman Institute for Molecular Biology, Jakarta, Indonesia
  74. 74. Department of Hepatitis and Emerging Infectious Diseases, University of Sydney, Sydney, Australia
  75. 75. Department of Gastroenterology, Fatima Memorial Hospital, College of Medicine and Dentistry, Shadman, Lahore, Pakistan
  76. 76. Direct. of Direct Transmitted Disease Control, Disease Control and Environmental Health, Ministry of Health, Jakarta, Indonesia
  77. 77. Pakistan Medical Research Council, Islamabad, Pakistan
  78. 78. Khawar Clinic, Sahiwal, Pakistan
  79. 79. Department of Gastroenterology, Military Hospital, Rawalpindi, Pakistan
  80. 80. Department of Hepatology and Gastroenterology, School of Medical Science, Saint Joseph University, Beirut, Lebanon
  81. 81. Jinnah Memorial Hospital, Rawalpindi, Pakistan
  82. 82. Yusra Medical College, Rawalpindi, Pakistan
  83. 83. Allama Iqbal Medical College, Lahore, Pakistan
  84. 84. Centre for Health Security and Communicable Disease Control, Direct. of Health in Iceland, Reykjavik, Iceland
  85. 85. Klinik Hati Prof. Ali Sulaiman, Jakarta, Indonesia
  86. 86. Health Funding Department, Enaya Insurance Company, Abu Dhabi, United Arab Emirates
  87. 87. Department of Medicine, Tawam Hospital, Al Ain, United Arab Emirates
  88. 88. Department of Epidemiology, Infectious Disease Control and Prevention, Hiroshima University, Institute of Biomedical and Health Sciences, Hiroshima, Japan
  89. 89. Pharmacy Department, Tawam Hospital, Al Ain, United Arab Emirates
  90. 90. Postgraduate Medical Institute, Lahore General Hospital, Lahore, Pakistan
  91. 91. Doctors Hospital and Medical Center, Lahore, Pakistan
  92. 92. Pakistan Society of Gastroenterology, Karachi, Pakistan
  93. 93. Department of Medicine, Rawalpindi Medical College, Rawalpindi, Pakistan
  94. 94. Department of Medicine, Holy Family Hospital, Rawalpindi, Pakistan
  95. 95. Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
  96. 96. Shaukat Khanum Memorial Cancer Hospital, Research Centre, Lahore, Pakistan
  97. 97. Dow Medical College, Karachi, Pakistan

Source: Journal of Viral Hepatitis Published:2015


Abstract

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries in Europe, the Middle East and Asia, and the relative impact of two scenarios was considered: increased treatment efficacy while holding the annual number of treated patients constant and increased treatment efficacy and an increased annual number of treated patients. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. A 90% reduction in total HCV infections within 15 years is feasible in most countries studied, but it required a coordinated effort to introduce harm reduction programmes to reduce new infections, screening to identify those already infected and treatment with high cure rate therapies. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. Among European countries, the majority of patients were born between 1940 and 1985. A wider range of birth cohorts was seen in the Middle East and Asia (between 1925 and 1995). © 2015 John Wiley & Sons Ltd.