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Cell-Based Approaches Towards Treating Age-Related Macular Degeneration Publisher Pubmed



Baradaranrafii A1, 2 ; Sarvari M3 ; Alavimoghadam S3 ; Payab M4 ; Goodarzi P5 ; Aghayan HR3 ; Larijani B6 ; Rezaeitavirani M7 ; Biglar M6 ; Arjmand B3, 8
Authors

Source: Cell and Tissue Banking Published:2020


Abstract

Age-related macular degeneration as one of the most common causes of worldwide vision loss needs a proper approach for treatment. Therein, cell therapy and regenerative medicine can hold a great promise to be an effective approach. Accordingly, some preclinical and clinical studies were conducted to search around the therapeutic influence of stem cells in Age-related macular degeneration models and subjects. Hereupon, the purpose of the current review is to discuss the mechanisms of age-related macular degeneration, appropriate animal models along with suitable dosage and route of stem cell administration for its treatment. © 2020, Springer Nature B.V.