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Generation of Mr-Based Attenuation Correction Map of Pet Images in the Brain Employing Joint Segmentation of Skull and Soft-Tissue From Single Short-Te Mr Imaging Modality Publisher



Kazerooni AF1, 3 ; Aarabi MH1, 3 ; Ay M2, 3 ; Rad HS1, 3
Authors
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Authors Affiliations
  1. 1. Quantitative MR Imaging and Spectroscopy Group, Research Center for Cellular and Molecular Imaging, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Medical Imaging Systems Group, Research Center for Cellular and Molecular Imaging, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Lecture Notes in Computational Vision and Biomechanics Published:2015


Abstract

Recently introduced PET/MRI scanners present significant advantages in comparison with PET/CT, including better soft-tissue contrast, lower radiation dose, and truly simultaneous imaging capabilities. However, the lack of an accurate method for generation ofMR-based attenuation map (μ-map) at 511 keV is hampering further development and wider acceptance of this technology. Here, we present a new method for the MR-based attenuation correction map (μ-map), employing a proposed short echo-time (STE) MR imaging technique along with the nearly automatic segmentation. This method repeatedly applies active contours inhomogeneity correction, multi-class spatial fuzzy clustering (SFCM), followed by shape analysis, to classify the images into cortical bone, air, and soft tissue classes. The proposed segmentation method returned sensitivity of 81% for cortical bone and above 90% for soft tissue and air. These results suggest that this technique is accurate, efficient, and robust for discriminating bony structures from the neighboring air and soft tissue in STE-MR images, which is suitable for generating MR-based μ-maps. © Springer International Publishing Switzerland 2015.