The Flexural Strength of Orthodontic Acrylic Resin Containing Resveratrol Nanoparticles As Antimicrobial Agent: An in Vitro Study Publisher



Bahrami R¹ ; Gharibpour F¹ ; Pourhajibagher M² ; Bahador A^{3, 4}
Source: International Orthodontics Published:2024

Abstract

Objective: This study aimed to evaluate how the addition of resveratrol nanoparticles (RNPs), which act as an antimicrobial agent, affects the strength of acrylic resin used in orthodontics. Methods: According to ISO 20795-1-2013, 76 cold cure acrylic resin samples (65 × 10 × 3.3 mm) were prepared. The samples were divided into four groups (19 samples in each group) based on RN concentrations added to 1 mL acrylic monomer (0 for control, 256, 512, and 1024 μg/mL). Flexural strength was assessed in megapascal (MPa) using a universal testing machine. Data analysis involved nonparametric Kruskal-Wallis analysis of variance and pairwise post-hoc Dunn's test. Results: The flexural strength decreased as the concentration of RNPs increased, with the lowest value observed at 1024 μg/mL (63.06 ± 5.33 MPa). The control group exhibited the highest mean of flexural strength (88.43 ± 4.41 MPa), followed by the groups with RNPs at the concentrations of 256 μg/mL (82.69 ± 4.41 MPa) and 512 μg/mL (76.02 ± 4.59 MPa). Conclusion: In conclusion, the addition of RNs to orthodontic acrylic resin had a dose-dependent impact on its flexural strength. Based on the findings, we recommend incorporating RNs at a concentration of 256 μg/mL as an antimicrobial agent in orthodontic acrylic resin. However, further research is necessary to assess the long-term effects and clinical applications of this approach. © 2024 CEO