Validation of the 15-Item Myasthenia Gravis Quality of Life Questionnaire (Mg-Qol15) Persian Version Publisher Pubmed



Ostovan VR¹ ; Fatehi F¹ ; Davoudi F² ; Nafissi S¹ Show Affiliations
Source: Muscle and Nerve Published:2016

Abstract

Introduction: The 15-item Myasthenia Gravis Quality Of Life (MG-QOL15) questionnaire is a valid and reliable instrument for evaluation of myasthenia gravis (MG) associated disability. Our study aim was to assess its validity and reliability in the Iranian population. Methods: We enrolled 75 consecutive patients with established MG at 2 neuromuscular clinics in Tehran, Iran. All 75 patients completed the Persian MG-QOL15 and SF-36 questionnaire initially, and 30 filled out the MG-QOL15 questionnaire from 2 to 4 weeks after the initial visit. Concurrent and construct validity, internal consistency, and test–retest repeatability of the questionnaire were evaluated. Results: The Persian MG-QOL15 showed satisfactory internal consistency (Cronbach alpha = 0.94) and test–retest reliability(r = 0.98; P < 0.001). It also demonstrated adequate concurrent and construct validity; moreover, the MG-QOL15 scores were higher in patients with more severe conditions. Conclusions: The Persian MG-QOL15 is a valid and reliable questionnaire for determination of quality of life in Iranian MG patients. Muscle Nerve 54: 65–70, 2016. © 2015 Wiley Periodicals, Inc.