Circulating Cell-Free Nucleic Acids As Potential Biomarkers for Sarcopenia: A Step Toward Personalized Medicine Publisher



Shafiee G¹ ; Heshmat R¹ ; Larijani B²
Source: Journal of Diabetes and Metabolic Disorders Published:2017

Abstract

Sarcopenia is an age-related loss of muscle mass and function, leading to disability, morbidity and increased mortality in older people. Given the relatively high prevalence and related- outcome of the disease, correct diagnosis, screening, monitoring and treatment of sarcopenia are needed in clinical practice. Recent researches have focused on cell-free nucleic acids, which are released into the circulation following cell death, as a potential biomarker of aging and systematic inflammation. It seems that the diagnosis and treatment of sarcopenia can be possible by the help of the analysis of cell-free nucleic acids as noninvasive method. © 2017 The Author(s).