Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?

Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration? Publisher Pubmed

Shirooie S¹ ; Nabavi SF^{2, 3} ; Dehpour AR^{4, 5} ; Belwal T⁶ ; Habtemariam S⁷ ; Arguelles S⁸ ; Sureda A⁹ ; Daglia M¹⁰ ; Tomczyk M¹¹ ; Sobarzosanchez E^{12, 13} ; Xu S¹⁴ ; Nabavi SM³

Source: Pharmacological Research Published:2018

Abstract

Neurodegenerative diseases (NDs) such as Parkinson's (PD), Alzheimer's (AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) cause significant world-wide morbidity and mortality. To date, there is no drug of cure for these, mostly age-related diseases, although approaches in delaying the pathology and/or giving patients some symptomatic relief have been adopted for the last few decades. Various studies in recent years have shown the beneficial effects of omega-3 poly unsaturated fatty acids (PUFAs) through diverse mechanisms including anti-inflammatory effects. This review now assesses the potential of this class of compounds in NDs therapy through specific action against the mammalian target of rapamycin (mTOR) signaling pathway. The role of mTOR in neurodegenerative diseases and targeted therapies by PUFAs are discussed. © 2018 Elsevier Ltd

Related Docs

1. Targeting Mtor With Curcumin: Therapeutic Implications for Complex Diseases, Inflammopharmacology (2025)

Style	Citing Format
MLA	Shirooie S, et al.. "Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?." Pharmacological Research, vol. 135, no. , 2018, pp. 37-48.
APA	Shirooie S, Nabavi SF, Dehpour AR, Belwal T, Habtemariam S, Arguelles S, Sureda A, Daglia M, Tomczyk M, Sobarzosanchez E, Xu S, Nabavi SM (2018). Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?. Pharmacological Research, 135(), 37-48.
Chicago	Shirooie S, Nabavi SF, Dehpour AR, Belwal T, Habtemariam S, Arguelles S, Sureda A, et al.. "Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?." Pharmacological Research 135, no. (2018): 37-48.
Harvard	Shirooie S et al. (2018) 'Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?', Pharmacological Research, 135(), pp. 37-48.
Vancouver	Shirooie S, Nabavi SF, Dehpour AR, Belwal T, Habtemariam S, Arguelles S, et al.. Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?. Pharmacological Research. 2018;135():37-48.
BibTex	@article{ author = {Shirooie S and Nabavi SF and Dehpour AR and Belwal T and Habtemariam S and Arguelles S and Sureda A and Daglia M and Tomczyk M and Sobarzosanchez E and Xu S and Nabavi SM}, title = {Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration?}, journal = {Pharmacological Research}, volume = {135}, number = {}, pages = {37-48}, year = {2018} }
RIS	TY - JOUR AU - Shirooie S AU - Nabavi SF AU - Dehpour AR AU - Belwal T AU - Habtemariam S AU - Arguelles S AU - Sureda A AU - Daglia M AU - Tomczyk M AU - Sobarzosanchez E AU - Xu S AU - Nabavi SM TI - Targeting Mtors by Omega-3 Fatty Acids: A Possible Novel Therapeutic Strategy for Neurodegeneration? JO - Pharmacological Research VL - 135 IS - SP - 37 EP - 48 PY - 2018 ER -

Science Communicator Platform

Authors

Abstract