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Outcomes of the Fluoroscopically-Guided Vs. Computed-Tomography-Guided Transforaminal Epidural Steroid Injection in Low Back Pain: A Propensity-Matched Prospective Cohort Publisher



Rafati A1 ; Ghanaati H2 ; Asadi B3 ; Mehrabi F3 ; Rahmatian A4 ; Hassani S5
Authors
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Authors Affiliations
  1. 1. School of Medicine, Aja University of Medical Sciences, Tehran, Iran
  2. 2. Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center, Medical Imaging Center, Imam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran
  3. 3. Department of Neurology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran
  4. 4. Faculty of Medicine, Department of Neurology, Ilam University of Medical Sciences, Ilam, Iran
  5. 5. Goddard Lab, Radiology Department, Penn Medical University, Philadelphia, PA, United States

Source: Medical Journal of the Islamic Republic of Iran Published:2023


Abstract

Background: Low back pain (LBP), the most common musculoskeletal condition, imposes a significant burden on healthcare and triggers mental and physical disorders. Before surgery, patients are eligible for minimally-invasive treatments, including transforaminal epidural steroid injection (TFESI). We aimed to compare fluoroscopically and CT-guided TFESI in patients with subacute (4-12 weeks) and chronic (≥12 weeks) LBP. Methods: In this prospective cohort study, 121 adults with subacute or chronic LBP were recruited. Using propensity score matching (PSM), we created two age, sex, and body mass index (BMI) matched groups of fluoroscopically and CT-guided TFESI, each including 38 patients. The outcomes of interest were the Oswestry disability index (ODI) and numerical rating scale (NRS), which were measured in all patients before the procedure and at the three-month follow-up. Then, the ODI and NRS mean changes were compared between Fluoroscopy and CT groups using repeated measures ANOVA. All analyses were performed with IBM SPSS Statistics for Windows, version 26 (IBM Corp., Armonk, NY, USA). Results: Of the total 76 matched patients with a mean (SD) age of 66.22 (13.49), 81 (66.9%) were female. ODI and NRS scores significantly decreased from baseline to the three-month follow-up in both treatment groups. The ODI score mean change from baseline to follow-up compared between the two groups was insignificant (fluoroscopy vs. CT mean difference (95% CI): 1.092 (- 0.333-2.518), P = 0.131). Similarly, the NRS score mean change from baseline to follow-up compared between the two groups was insignificant (fluoroscopy vs. CT mean difference (95% CI): -0.132 (-0.529-0.265), P = 0.511). Conclusion: Fluoroscopically and CT-guided TFESI show similar therapeutic effectiveness in patients with subacute and chronic LBP © Iran University of Medical Sciences
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