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Psychometric Evaluation of the Hamilton Inventory to Evaluate Signs and Symptoms in Patients With Complex Regional Pain Syndrome (Crps) Publisher



Farzad M1, 2 ; Packham T3 ; Macdermid J1, 4 ; Mohammadi F2 ; Hosseini SA5 ; Kamrani RS6 ; Shariatzadeh H7 ; Koushan A6 ; Kalantar SH8 ; Bakhshi E2
Authors
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Authors Affiliations
  1. 1. Hand and Upper Limb Center, St. Joseph's Health Center, School of Physical Therapy, Department of Health and Rehabilitation Sciences, University of Western Ontario, London, ON, Canada
  2. 2. School of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  3. 3. School of Rehabilitation Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
  4. 4. Physical Therapy and Surgery, Western University, London, ON, Canada
  5. 5. Social Determination of Health Research Center, School of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  6. 6. Hand Surgery Department, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
  8. 8. Joint Reconstruction Research Center, IKHC, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Hand Therapy Published:2025


Abstract

Background: Complex Regional Pain Syndrome (CRPS) is a debilitating condition with profound physical and psychological impacts, necessitating comprehensive assessment tools for effective evaluation. Purpose: This study aimed to validate the Persian version of the Hamilton Inventory for Complex Regional Pain Syndrome (HI-CRPS) and assess its reliability and validity in individuals diagnosed with CRPS. Study Design: A cross-sectional clinical measurement study evaluated the Persian version of HI-CRPS. Methods: A sample of 64 individuals diagnosed with CRPS from pain and hand surgeon clinics completed the Persian versions of the patient-reported (PR-HI-CRPS) and clinicians based (CB-HI-CRPS). Test-retest reliability was assessed after 1 week, and responsiveness was measured after 3 months. Baseline scores, ceiling effects, internal consistency (Cronbach's alpha), and construct validity (correlations with related measures) were examined. Effect sizes and standardized response means (SRM) were calculated to gauge responsiveness. Results: Baseline scores for PR-HI-CRPS and CB-HI-CRPS were 77.8 and 14.9, respectively. Around 18% of PR-HI-CRPS and 16% of CB-HI-CRPS respondents exhibited ceiling effects. Internal consistency for PR-HI-CRPS (Cronbach's alpha: 0.71–0.91) and CB-HI-CRPS (alpha: 0.90) was satisfactory. PR-HI-CRPS (ICC: 0.86) and CB-HI-CRPS (ICC: 0.97) showed robust test-retest reliability. Construct validity was confirmed by significant correlations between PR-HI-CRPS subscales and related measures (p < 0.01). Structural validity was confirmed by confirmatory factor analysis. PR-HI-CRPS displayed an effect size of 0.79 and a standardized response mean (SRM) of 0.88. Conclusions: The Persian version of the HI-CRPS demonstrated satisfactory internal consistency, test-retest reliability, construct validity, and responsiveness. It can be relied upon to assess CRPS symptoms, functional limitations, and psychosocial impacts. © 2025 The Authors
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