A Rare Case of Hyper Ige Syndrome With Vocal Cords Involvement Publisher Pubmed



Sharafian S¹ ; Movahedi M² ; Kalantari A³ ; Parvaneh N² ; Gharagozlou M²
Source: Iranian Journal of Allergy# Asthma and Immunology Published:2019

Abstract

Hyperimmunoglobulin E syndrome (HIGE) is considered as a phagocytic or a newly classified complex and heterogeneous primary immunodeficiency disease with symptoms such as increased levels of immunoglobulin E, eczema, and, recurrent lung and skin infections. In this paper, we have presented a rare case of this syndrome. A 9-year-old Iranian girl presented with a history of pruritic maculopapular rash who was eventually diagnosed as a case of HIGE. In her recent admission, she had dysphonia, stridor and huge cauliflower cutaneous lesions on her neck, finger and vocal cords, which did not respond to intravenous antibiotics, and ultimately required surgical removal. Copyright© April 2019, Iran J Allergy Asthma Immunol. All rights reserved.