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Aspheric Versus Wavefront-Guided Photorefractive Keratectomy: Contralateral Eye Study Publisher Pubmed



Zareighanavati S1 ; Gharaee H1 ; Hamilton DR3 ; Sanchez PJ3 ; Abrishami M2
Authors
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Authors Affiliations
  1. 1. Cornea Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Laser Refractive Center, School of Medicine, University of California Los Angeles, Los Angeles, CA, United States

Source: Journal of Cataract and Refractive Surgery Published:2015


Abstract

Purpose To compare the refractive, visual, and aberrometric outcomes between wavefront-guided photorefractive keratectomy (PRK) and aspheric PRK in myopic patients. Setting Khatam-al-Anbia Eye Hospital, Mashhad, Iran. Design Prospective randomized clinical trial. Methods One eye of each patient was randomly assigned to excimer laser wavefront-guided PRK (Zyoptix) and the other eye to excimer laser aspheric PRK (Technolas 217z). The preoperative and 3-month and 6-month postoperative refractive errors, visual acuity, contrast sensitivity, and higher-order aberrations (HOAs) were compared between the groups. Results Ninety-six eyes (48 patients) were enrolled. At the last postoperative visit, there were no between-group differences in uncorrected distance visual acuity (UDVA) (P =.987) or corrected distance visual acuity (P =.416). The mean spherical equivalent was -0.076 diopter (D) ± 0.029 (SD) in the wavefront-guided group and -0.077 ± 0.075 D in the aspheric PRK group (P =.684). Postoperatively, the mean area under the log of contrast sensitivity function (AULCSF) with and without glare testing improved over preoperative values (both P <.001). There was no statistically significant between-group difference in the AULCSF with glare (P =.903) or without glare (P =.978). Total HOAs increased after PRK in both groups, although aspheric PRK induced fewer HOAs than wavefront-guided PRK (P =.04). Conclusions Both PRK methods equally improved postoperative UDVA and contrast sensitivity. The HOAs increased after treatment with both methods; however, aspheric ablation induced statistically fewer HOAs than wavefront-guided ablation. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. © 2015 ASCRS and ESCRS.