Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]

Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته] Publisher

Tajabadi F¹ ; Rezazadeh S¹ ; Ghasemi SV¹ ; Abedinpour M² ; Sharifi M² ; Hamedani MP³ ; Jamshidi A⁴ ; Yazdani D¹

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1. Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran
2. Pharmaceutical Sciences Branch Faculty of Pharmacy, Islamic Azad University, Tehran, Iran
3. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran

Source: Journal of Medicinal Plants Published:2022

Abstract

Background: Post-market surveillance (PMS) is an integral part of ongoing safety evaluation, for natural health products. Matricaria chamomilla (chamomile) and Thymus vulgaris (thyme) are the most widely used plants in herbal medicinal products. Thymus species contain phenolic compounds such as thymol, carvacrol and terpenoids, flavonoids, and saponins. T. vulgaris is an antiseptic and antitussive, so it is very effective in treating dry coughs, colds, and inflammation of the upper respiratory tract. Matricaria chamomilla (chamomile) products containing apigenin-7-glycoside, some flavonoids and chamazulene in its essential oil that have anti-inflammatory, anti-fungal and anti-bacterial therapeutic properties. Objective: In this study, various dosage forms containing thyme (8 products) and chamomile (9 products) separately, (which are available in the form of drops, syrups, ointments, and creams) were provided. Then, physicochemical controls were performed based on the reference methods of herbal pharmacopeias and in-house validated methods to ensure quality and stability of these products. Methods: Since many of these products have no special monograph in pharmacopeias, so validated extraction and analysis methods were developed to quantify the apigenin-7-glycoside by high performance liquid chromatography, and chamazulene by gas chromatography in the chamomile products and thymol and carvacrol by gas chromatography in thyme products in different complex dosage forms. Results: In some products that formulated by thyme and chamomile products, the amount reported for standardization does not match the values obtained. Conclusion: It's recommended more control of herbal medicines for appropriate and effective consumption of them. © 2020. Open access. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/)

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Style	Citing Format
MLA	Tajabadi F, et al.. "Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]." Journal of Medicinal Plants, vol. 21, no. 84, 2022, pp. 13-25.
APA	Tajabadi F, Rezazadeh S, Ghasemi SV, Abedinpour M, Sharifi M, Hamedani MP, Jamshidi A, Yazdani D (2022). Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]. Journal of Medicinal Plants, 21(84), 13-25.
Chicago	Tajabadi F, Rezazadeh S, Ghasemi SV, Abedinpour M, Sharifi M, Hamedani MP, Jamshidi A, Yazdani D. "Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]." Journal of Medicinal Plants 21, no. 84 (2022): 13-25.
Harvard	Tajabadi F et al. (2022) 'Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]', Journal of Medicinal Plants, 21(84), pp. 13-25.
Vancouver	Tajabadi F, Rezazadeh S, Ghasemi SV, Abedinpour M, Sharifi M, Hamedani MP, et al.. Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]. Journal of Medicinal Plants. 2022;21(84):13-25.
BibTex	@article{ author = {Tajabadi F and Rezazadeh S and Ghasemi SV and Abedinpour M and Sharifi M and Hamedani MP and Jamshidi A and Yazdani D}, title = {Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته]}, journal = {Journal of Medicinal Plants}, volume = {21}, number = {84}, pages = {13-25}, year = {2022} }
RIS	TY - JOUR AU - Tajabadi F AU - Rezazadeh S AU - Ghasemi SV AU - Abedinpour M AU - Sharifi M AU - Hamedani MP AU - Jamshidi A AU - Yazdani D TI - Post-Marketing Control of Matricaria Chamomilla L. and Thymus Vulgaris L. Products by Reference and Developed Methods; [کنترل پس از ورود به بازار محصولات بابونه و آویشن با روشهای مرجع و توسعه یافته] JO - Journal of Medicinal Plants VL - 21 IS - 84 SP - 13 EP - 25 PY - 2022 ER -

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