Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]

Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز] Publisher

Tavakoli S¹ ; Khalighisigaroodi F¹ ; Dehaghi NK^{2, 3} ; Yaghoobi M⁴ ; Hajiaghaee R¹ ; Gholami A⁵ ; Ghafarzadegan R¹

Source: Journal of Medicinal Plants Published:2022

Abstract

Background: Flavonoids, a group of natural substances, are found in flowers, fruits, roots and stems. These natural products are well known for their health-beneficial effects. Hence, isolation and purifying of flavonoids from the ingredients is worthwhile. Flavonoids are now considered indispensable in various nutraceutical, pharmaceutical, medicinal and cosmetic applications. Apigenin, quercetin, and apigenin-7-O-glycoside have therapeutic properties that these two are in the flavonoid group. Objectives: In this study, apigenin, quercetin, and apigenin 7-O-glycoside were purified by column chromatography and identified by NMR and HPLC UV-visible techniques. Methods: Total extracts of three plants (Apium graveolens, Petroselinum crispum, Allium cepa) were divided into different solvent fractions. Column chromatography is used to purify these fractions. Finally, 1H-NMR, 13C-NMR, and mass spectrometry techniques were used for identification. Also, the HPLC technique was used for identifying these compounds and standardized. Results: In the present work, apigenin was extracted from ethyl acetate fraction of Apium graveolens seeds. High purity of apigenin 7-O-glycoside isolated from the butanol fraction of Petroselinum crispum aerial parts. Also, ethyl acetate fraction isolated quercetin from the Allium cepa. Identification of the data obtained from 1H-NMR and 13C-NMR, which were proofed by comparison with the sources of purified compounds. Conclusion: The methods used in this research were able to produce these three compounds with a high percentage of purity to be used in industry as standards. © 2020. Open access. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/)

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Style	Citing Format
MLA	Tavakoli S, et al.. "Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]." Journal of Medicinal Plants, vol. 21, no. 83, 2022, pp. 72-86.
APA	Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, Ghafarzadegan R (2022). Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]. Journal of Medicinal Plants, 21(83), 72-86.
Chicago	Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, Ghafarzadegan R. "Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]." Journal of Medicinal Plants 21, no. 83 (2022): 72-86.
Harvard	Tavakoli S et al. (2022) 'Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]', Journal of Medicinal Plants, 21(83), pp. 72-86.
Vancouver	Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, et al.. Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]. Journal of Medicinal Plants. 2022;21(83):72-86.
BibTex	@article{ author = {Tavakoli S and Khalighisigaroodi F and Dehaghi NK and Yaghoobi M and Hajiaghaee R and Gholami A and Ghafarzadegan R}, title = {Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]}, journal = {Journal of Medicinal Plants}, volume = {21}, number = {83}, pages = {72-86}, year = {2022} }
RIS	TY - JOUR AU - Tavakoli S AU - Khalighisigaroodi F AU - Dehaghi NK AU - Yaghoobi M AU - Hajiaghaee R AU - Gholami A AU - Ghafarzadegan R TI - Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز] JO - Journal of Medicinal Plants VL - 21 IS - 83 SP - 72 EP - 86 PY - 2022 ER -

Style

Citing Format

MLA

Tavakoli S, et al.. "Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]." Journal of Medicinal Plants, vol. 21, no. 83, 2022, pp. 72-86.

APA

Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, Ghafarzadegan R (2022). Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]. Journal of Medicinal Plants, 21(83), 72-86.

Chicago

Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, Ghafarzadegan R. "Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]." Journal of Medicinal Plants 21, no. 83 (2022): 72-86.

Harvard

Tavakoli S et al. (2022) 'Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]', Journal of Medicinal Plants, 21(83), pp. 72-86.

Vancouver

Tavakoli S, Khalighisigaroodi F, Dehaghi NK, Yaghoobi M, Hajiaghaee R, Gholami A, et al.. Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]. Journal of Medicinal Plants. 2022;21(83):72-86.

BibTex

@article{ author = {Tavakoli S and Khalighisigaroodi F and Dehaghi NK and Yaghoobi M and Hajiaghaee R and Gholami A and Ghafarzadegan R}, title = {Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]}, journal = {Journal of Medicinal Plants}, volume = {21}, number = {83}, pages = {72-86}, year = {2022} }

RIS

TY - JOUR
AU - Tavakoli S
AU - Khalighisigaroodi F
AU - Dehaghi NK
AU - Yaghoobi M
AU - Hajiaghaee R
AU - Gholami A
AU - Ghafarzadegan R
TI - Isolation and Purification of Apigenin, Quercetin and Apigenin 7-O-Glycoside From Apium Graveolens L., Petroselinum Crispum (Mill.) Fuss, Allium Cepa L., Respectively; [گلیکوزید به ترتیب از گیاهان کرفس،-O- خالصسازی و شناسایی آپیژنین، کوئرستین، آپیژنین 7جعفری و پیاز]
JO - Journal of Medicinal Plants
VL - 21
IS - 83
SP - 72
EP - 86
PY - 2022
ER -

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