Comparison of Quince With Vitamin B6 for Treatment of Nausea and Vomiting in Pregnancy: A Randomised Clinical Trial Publisher Pubmed



Jafaridehkordi E¹ ; Hashemdabaghian F¹ ; Aliasl F² ; Aliasl J¹ ; Taghavishirazi M¹ ; Sadeghpour O¹ ; Sohrabvand F³ ; Minaei B⁴ ; Ghods R¹ Show Affiliations
Source: Journal of Obstetrics and Gynaecology Published:2017

Abstract

This trial was performed to compare quince (Cydonia oblonga) fruit with vitamin B6 on 76 pregnant women with a gestational age of 6–14 weeks and mild-to-moderate nausea and vomiting (NVP) (40 in the quince and 36 in the B6 group). The ‘Pregnancy-Unique Quantification of Emesis’ (PUQE-24) scale was used to examine the severity of NVP. The quince syrup (1 tablespoon/TDS) or vitamin B6 tablets (20 mg/TDS) were used as intervention for 1week. The mean (±SD) age was 27.5 (±5.2) years. The score of the PUQE was decreased from 9.5 (± 2) at baseline to 5.2 (±2.3) on the 7th day and 5.3 (±2.6) on the 14th day (p<.001) in the quince group. In the other group, the scores were 8.4 (±1.8), 7.3 (±2.4) and 7.7 (±3.8), respectively (p=.001). The change in symptoms were more marked in the quince group (p<.001). Quince syrup seems to be a suitable treatment for NVP. © 2017 Informa UK Limited, trading as Taylor & Francis Group.