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Synthesis of Heterocycles by Utilizing Phthalaldehydic Acid: An Overview Publisher



Sheykhi S1 ; Pedrood K2 ; Amanlou M1 ; Larijani B2 ; Mahdavi M2
Authors
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Authors Affiliations
  1. 1. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Tetrahedron Published:2022


Abstract

In this review, the construction of polycyclic compounds by taking advantage of phthaldehydic acid as a starting material has been explained. The in-depth description about recent several reactions applied with phthaldehydic acid and their mechanism to synthesize these various heterocycles have been mentioned and compared thoroughly as well. The major goal of this review is to introduce the latest advances about using phthaldehydic acid in various reactions to construct a plethora of novel polycyclic structures expected to be bioactive compounds. © 2022 Elsevier Ltd