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Comparison of the Diagnostic Accuracy of Contrast-Enhanced/Dwi Mri and Ultrasonography in the Differentiation Between Benign and Malignant Myometrial Tumors Publisher



Najibi S1 ; Gilani MM2 ; Zamani F3 ; Akhavan S2 ; Zamani N2
Authors
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Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Gynecologic Oncology, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Radiology, Children Medical Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran

Source: Annals of Medicine and Surgery Published:2021


Abstract

Background: Various modalities including ultrasonography and magnetic resonance imaging (MRI) have been developed as imaging technique for screening malignant myometrial tumors, but a few studies assessed the diagnostic value of these two techniques in differentiation of benign from malignant myometrial tumors that had been the main purpose of this study. Materials and methods: This cross-sectional study was performed on 63 women underwent surgery for intrauterine masses that were initially assessed using MRI and ultrasound before surgery at a tertiary hospital in Tehran from 2016 to 2020. Their MRI was reviewed by a reputable radiologist in the field. The findings of histopathological assessment were considered as the gold diagnostic standard. Results: The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI to detect sarcoma were revealed to be 94.6%, 92.3%, 94.6%, 92.3%, and 93.7% respectively. Ultrasonography had not preferable applicability to differentiate sarcoma from benign tumors with sensitivity, specificity, PPV, NPV and accuracy of 35.1%, 88.4%, 81.2%, 48.9%, and 57.1% respectively. The diagnostic performance of both modalities was not affected by baseline clinical conditions including pain, abnormal uterine bleeding and menopausal status. Conclusion: MRI but not ultrasonography can effectively differentiate benign from malignant myometrial tumors. © 2021