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Psychogenic Non-Epileptic Seizures; a Narrative Review Publisher



Jafari A1 ; Tavirani MR2 ; Hamrah MP2 ; Karvigh SA3 ; Fakhar HB4
Authors
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Authors Affiliations
  1. 1. Student Research Committee, Proteomics Research Center, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Proteomics Research Center, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of laboratory science, chalous branch, islamic azad University, chalous, Iran

Source: Archives of Academic Emergency Medicine Published:2020


Abstract

Psychogenic non-epileptic seizures (PNES) are paroxysmal changes that mimic epileptic seizures, so often mis-diagnosed and treated for epilepsy. PNES are considered a psychiatric illness, personality pathology, and experiential and behavioral manifestation of depression. Despite studies over the past two decades, the pathological mechanisms of this disorder are unclear. In this paper, we critically review the current literature about the definition, epidemiology, diagnosis, treatment, related genes, and biomarkers of PNES and provide suggestions for future research. Further studies are needed for more information and knowledge on PNES to determine the appropriate psychotherapies and development of clear treatment guidelines. © 2020, Archives ofAcademic Emergency Medicine. All Rights Reserved