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Combination of Fractional Radiofrequency and Thermo-Contraction Systems for Facial Skin Rejuvenation: A Clinical and Histological Study Publisher Pubmed



Samadi A1 ; Nasrollahi SA1 ; Janani L2 ; Moosavi ZB1 ; Hesari KK3 ; Kalantari AR4 ; Firooz A1
Authors
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Authors Affiliations
  1. 1. Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, #415 Taleqani Ave, Tehran, Iran
  2. 2. Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Dermatopatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. CEO of Medaria, Tehran, Iran

Source: Aesthetic Surgery Journal Published:2018


Abstract

Background: Radiofrequency energy systems are popular options in the treatment of skin laxity and wrinkles. Fractional radiofrequency devices (FRFs) have increased the efficacy and safety. The thermo-contraction (TC) system is also a novel technology that can promote a marked lifting effect. Objectives: This trial was done to assess the safety and efficacy of a combination treatment using the FRF system and TC for facial skin rejuvenation. Methods: Fifteen female volunteers (mean age, 47.07 ± 8.83 years) received 3 FRF and 6 TC bipolar treatments in 3 weeks. Assessment methods included wrinkle grading by independent investigator using Glogau wrinkle scoring, objective measurement of depth, area, and volume of right nasolabial fold (using the VisioFace CSI software), thickness and echo-density of the dermis (using high-frequency ultrasound), and measurement of the skin biophysical parameters before and 3 months after last treatment. Histological assessment was also performed on 5 volunteer participants. Results: The clinical evaluation showed a significant improvement in Glogau wrinkle scoring after 3 months (P value, 0.041). The area and volume of nasolabial folds were also significantly reduced (P values, 0.026 and 0.031, respectively). Skin ultrasound showed a significant increase in echo-density of the dermis, which was confirmed by histological findings of an increase in dermal collagen content. Adverse reactions were all transient and mild in severity, and subjects were “moderately satisfied” with the treatment (Likert scale, 3.6 out of 5). Conclusions: The results of this trial showed that a combination therapy by FRF and TC bipolar systems is efficient and safe for facial skin rejuvenation. © 2018 The American Society for Aesthetic Plastic Surgery, Inc.