Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Utility of the Cha2ds2-Vasc Score in Prediction of Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft Surgery Publisher Pubmed



Mortazavi SH1 ; Oraii A1 ; Goodarzynejad H1 ; Bina P1 ; Jalali A1 ; Ahmadi Tafti SH1 ; Bagheri J1 ; Sadeghian S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Cardiothoracic and Vascular Anesthesia Published:2022


Abstract

Objective: The authors aimed to investigate the role of CHA2DS2-VASc score and its components in prediction of postoperative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. Design: Retrospective cohort. Setting: Single-center university-affiliated tertiary cardiac center. Participants: A total of 2,981 consecutive patients who underwent isolated CABG between 2010 and 2012 were included. Interventions: All patients underwent isolated CABG and were followed until discharge or in-hospital death. The primary outcome was the development of new-onset POAF during the hospital course. Measurements and Main Results: During hospitalization, continuous electrocardiogram monitoring was used to detect POAF episodes. New-onset POAF developed in 15.8% of patients following isolated CABG. Patients with POAF had significantly higher CHA2DS2-VASc scores than those without POAF (2.66 ± 1.51 v 2.12 ± 1.36, p < 0.001). After adjustment for potential confounders, CHA2DS2-VASc score was significantly associated with POAF (odds ratio [OR]: 1.295, 95% CI: 1.205-1.391). However, further analyses showed that this effect was restricted to patients with a CHA2DS2-VASc score of ≥2 (OR: 1.813, 95% CI: 1.220-2.694). In multivariate analysis of the CHA2DS2-VASc components, age ≥75 (OR: 3.737, 95% CI: 2.702-5.168), age 65 to 74 (OR: 2.126, 1.701-2.658), hypertension (OR: 1.310, 95% CI: 1.051-1.633), and cerebrovascular accident (OR: 1.807, 95% CI: 1.197-2.726) were independent predictors of POAF. However, the association between POAF and female sex, diabetes mellitus, congestive heart failure, and vascular disease was not statistically significant. Conclusions: CHA2DS2-VASc score is a useful tool for the prediction of POAF after isolated CABG. However, the risk should be interpreted cautiously, since the risk score's promising effect relies on only several of its components. © 2021 Elsevier Inc.
Related Docs
1. Left Atrial Size; a Missing Component in Scoring Systems for Predicting Atrial Fibrillation Following Coronary Artery Bypass Surgery, Acta Cardiologica Sinica (2020)
2. Update on the Efficacy of Statins in Primary and Secondary Prevention of Atrial Fibrillation; [Atualizacoes Sobre a Eficacia Das Estatinas Na Prevencao Primaria E Secundaria Da Fibrilacao Auricular], Revista Portuguesa de Cardiologia (2021)
3. Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review, JAMA Cardiology (2022)
4. Randomized Trial of Carnitine for the Prevention of Perioperative Atrial Fibrillation, Seminars in Thoracic and Cardiovascular Surgery (2018)
5. Waist Circumference and Body Surface Area and the Risk of Developing New-Onset Atrial Fibrillation: A Systematic Review and Meta-Analysis of Observational Studies, Heart and Lung (2025)
6. Cha2ds2-Vasc Score As an Independent Predictor of Suboptimal Reperfusion and Short-Term Mortality After Primary Pci in Patients With Acute St Segment Elevation Myocardial Infarction, Medicina (Lithuania) (2019)
7. Perioperative Cardiac Troponin T and Risk of Postoperative Atrial Fibrillation in Coronary Artery Bypass Graft Surgery, Critical Pathways in Cardiology (2022)
Experts (# of related papers)
View all Related Experts
Arash Jalali (3)
Kyomars Abbasi (2)