Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Facile One-Pot Synthesis of Spiroacenaphthylene Derivatives Using Sba-Pr-Nh2 Publisher



Ziarani GM1 ; Hajiabbasi P1 ; Badiei A2 ; Amanlou M3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Chemistry, Alzahra University, Vanak Square, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Department of Medicinal Chemistry, Drug Design and Development Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of the Chilean Chemical Society Published:2015


Abstract

A simple procedure afforded novel spiroacenaphthylene derivatives in high yields at room temperature from acenaphthenequinone, malononitrile, and phenol derivatives using amino-functionalized silica (SBA-Pr-NH2) as a heterogeneous efficient solid base catalyst. Using SBA-Pr-NH2 in the current procedure presents several advantages, such as a simpler procedure, shorter reaction times, facile synthesis, and simpler work-up. Also, recycling of the catalyst was completed with no significant decrease in the activity of catalyst.