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Photochemical Regioselective C-H Arylation of Imidazo[1,2-A]Pyridine Derivatives Using Chlorophyll As a Biocatalyst and Diazonium Salts Publisher



Moazzam A1 ; Farid SM1 ; Khaleghi N1 ; Alizadeh N1 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: New Journal of Chemistry Published:2022


Abstract

This communication describes the development of a mild method for the arylation of imidazo[1,2-a]pyridine with diazonium salt derivatives and using chlorophyll as a biocatalyst via visible-light catalysis. Natural pigments such as chlorophyll are used as a green photosensitizer and an environmentally benign catalyst. The general and easy procedure provides a transition-metal-free alternative for the formation of 2,3-diaryl imidazo[1,2-a]pyridine derivatives at ambient temperature in good to excellent yields. © 2022 The Royal Society of Chemistry