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Fatal Necrotising Cutaneous Mucormycosis Due to Novel Saksenaea Species: A Case Study Publisher Pubmed



Kachuei R1 ; Badali H2, 3 ; Vaezi A4 ; Jafari NJ5 ; Ahmadikia K6 ; Kord M6 ; Aala F7 ; Alhatmi AMS8, 9, 10 ; Khodavaisy S6
Authors
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Authors Affiliations
  1. 1. Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
  2. 2. Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
  3. 3. Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  4. 4. Department of Medical Laboratory Science, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
  6. 6. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Parasitology and Mycology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
  8. 8. Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands
  9. 9. Directorate General of Health Services, Ministry of Health, Oman
  10. 10. Centre of Expertise in Mycology, Radboud University Medical Centre, Canisius Wilhelmina Hospital, Nijmegen, Netherlands

Source: Journal of Wound Care Published:2021


Abstract

This case report describes the progressive wound infection in the left thigh of a 34-year-old man due to an old landmine explosion. The infection developed into rapidly spreading skin and soft tissue necrotising Saksenaea infection, despite antifungal therapy and surgical debridement. The report provides evidence that Saksenaea spp. should be added to the list of mucoralean fungi that can cause severe necrotising infection. It also highlights the need for improved early diagnostic procedures and enhanced understanding of Saksenaea virulence factors that contribute to necrotising infection. Declaration of interest: The authors have no conflicts of interest to declare. © 2021 MA Healthcare Ltd. All rights reserved.
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