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Essential Oil Composition and Antibacterial Activity of Levisticum Officinale Koch at Different Developmental Stages Publisher



Miran M1 ; Monsef Esfahani H1 ; Moridi Farimani M2 ; Ahmadi AA3 ; Ebrahimi SN2
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., Evin, Tehran, Iran
  3. 3. Department of Biology, Medicinal Plants Drugs Research Institute, Shahid Beheshti University, G.C., Evin, Tehran, Iran

Source: Journal of Essential Oil-Bearing Plants Published:2018


Abstract

GC-FID and GC-MS analyzed the essential oil composition obtained by hydrodistillation from aerial parts and roots of Levisticum officinale W.D.J. Koch at flowering and fruiting stages. The oils obtained in yields 2.5-3.0 % (v/w). The analysis of data resulted in the identification of twenty-eight compounds. The major compounds of oil from the aerial parts at flowering and fruiting stages were pentyl cyclohexa-1,3-diene (22.7-28.1 %), Z-ligustilide (24.5-26 %), neocnidilide (15.9-23 %). the β-phellandrene was in high percentages in roots. The components of oil from root at flowering and fruiting stages were Z-β-ocimene (13-28.1 %), Z-ligustilide (0.8-5.8 %), neocnidilide (4.8-11.6 %), p-menth-1-en-8-ol acetate (21.1-42.1 %) and pentyl cyclohexa-1,3-diene (2.2-2.4 %). The biological activity of essential oils was studied against two Gram-positive (Staphylococcus aureus and Entrococcus faecium) and two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) strains. The essential oil from the aerial parts at fruiting stage showed activity against S. aureus (MIC = 2.0 mg/ml), E. faecium (MIC = 8.0 mg/ml) and E. coli (MIC = 4.0 mg/ml). © 2018, © 2018 Har Krishan Bhalla & Sons.