Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial

Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial Publisher Pubmed

Zarei R¹ ; Azimi A^{1, 2} ; Fakhraei G¹ ; Eslami Y¹ ; Naderan M¹ ; Nourimahdavi K³ ; Caprioli J³

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1. Glaucoma service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3. Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, United States

Source: Eye (Basingstoke) Published:2023

Abstract

Background/Objective: Management of concomitant cataract and glaucoma depends on the stage of glaucoma and the patient’s situation. There are different surgical options for handling visually significant cataract and mild-to-moderate open-angle glaucoma (OAG). We aimed to compare the one-year results of phacoemulsification alone versus phacoviscocanalostomy in these patients. Subjects/Methods: This was a parallel-arm, single-masked, randomized-controlled trial, conducted at Farabi Eye Hospital, Tehran, Iran between January 2016 and January 2018. We enrolled 89 eyes from 89 patients with mild-to-moderate primary OAG or pseudoexfoliative glaucoma (PEXG) with visually significant age-related cataract. They randomly underwent phacoemulsification alone (n = 44) or combined phaco-viscocanalostomy (n = 45). All patients had a 12-month follow-up period, and the mean intraocular pressure (IOP), the number of antiglaucoma medications, and complete and qualified success rates were compared. Results: After the 1st and 3rd months, the mean IOP showed significantly decreased in the phaco-visco group compared to the phaco group (P < 0001 and P = 0.004, respectively), but it was not statistically significant at 6th and 12th months (P = 0.540 and P = 0.530). The need for antiglaucoma medication and the complete and qualified success rates were significantly in favour of the phaco-visco group in all postoperative visits (P < 0.05). Conclusions: Although both phacoemulsification alone and phacoviscocanalostomy procedures can be considered for patients with mild-to-moderate OAG, we found better success rates using phacoviscocanalostomy. Therefore, if the surgeon is an expert in performing this technique, this non-penetrating procedure can be applied in patients with visually significant cataract and earlier stages of OAG, especially in patients with PEXG. © 2022, The Author(s), under exclusive licence to The Royal College of Ophthalmologists.

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Experts (# of related papers)

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Masoud Mohammadi (2)

Ghasem Fakhraie (2)

Style	Citing Format
MLA	Zarei R, et al.. "Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial." Eye (Basingstoke), vol. 37, no. 7, 2023, pp. 1390-1396.
APA	Zarei R, Azimi A, Fakhraei G, Eslami Y, Naderan M, Nourimahdavi K, Caprioli J (2023). Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial. Eye (Basingstoke), 37(7), 1390-1396.
Chicago	Zarei R, Azimi A, Fakhraei G, Eslami Y, Naderan M, Nourimahdavi K, Caprioli J. "Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial." Eye (Basingstoke) 37, no. 7 (2023): 1390-1396.
Harvard	Zarei R et al. (2023) 'Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial', Eye (Basingstoke), 37(7), pp. 1390-1396.
Vancouver	Zarei R, Azimi A, Fakhraei G, Eslami Y, Naderan M, Nourimahdavi K, et al.. Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial. Eye (Basingstoke). 2023;37(7):1390-1396.
BibTex	@article{ author = {Zarei R and Azimi A and Fakhraei G and Eslami Y and Naderan M and Nourimahdavi K and Caprioli J}, title = {Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial}, journal = {Eye (Basingstoke)}, volume = {37}, number = {7}, pages = {1390-1396}, year = {2023} }
RIS	TY - JOUR AU - Zarei R AU - Azimi A AU - Fakhraei G AU - Eslami Y AU - Naderan M AU - Nourimahdavi K AU - Caprioli J TI - Combined Phacoviscocanalostomy Versus Phacoemulsification Alone in Patients With Coexisting Cataract and Mild-To-Moderate Open-Angle Glaucoma; a Randomized-Controlled Trial JO - Eye (Basingstoke) VL - 37 IS - 7 SP - 1390 EP - 1396 PY - 2023 ER -

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