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Validity and Reliability Assessment of the Persian Version of Therapy-Related Symptom Checklist Pubmed



Mansouri A1 ; Motaghedi R2 ; Rashidian A3 ; Ashouri A4 ; Kagrar M1 ; Hajibabaei M1 ; Gholami K1 ; Ansari S5
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Authors Affiliations
  1. 1. Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Pharmacy, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Global Health and Public Policy, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Health, Guilan University of Medical Sciences, Rasht, Iran
  5. 5. Department of Hematology and Oncology, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Medical Sciences Published:2017


Abstract

Therapy-related symptom checklist for children (TRSC-C) was developed as a symptom assessment tool in children receiving chemotherapy. The objective of the present study was to evaluate the validity and reliability of the Persian version of TRSC-C. This cross-sectional study was conducted in 2013-2014 in Tehran, Iran. TRSC-C was translated using backward-forward approach. The content validity, face validity, and comprehensiveness were investigated based on the opinion of experts. The item content validity index (I-CVI) and scale content validity index (S-CVI) were calculated by the mean approach and inter-rater agreement. The scale was revised based on the comments from a team of five experts, after which it was evaluated by an additional group of four experts. To assess the inter-rater reliability, two raters filled the scale with 29 and 30 patients in the outpatient clinic of Hazrat-e Ali Asghar Hospital. The Cronbach’s alpha was calculated and factor analysis was performed. The scores of content validity were analyzed in Excel. Other statistical analyses were performed using the SPSS software version 20.0. Based on the initial assessment, the S-CVI with less conservative approach was 60% for clarity, 33% for relevancy, and 60% for simplicity. After revising the scale, the S-CVI reached 100%. The comprehensiveness and face validity of the scale were appropriate. The scale was inter-rater reliable and the Cronbach’s alpha was 0.803. Eleven subscales were found in the TRSC-C. It is concluded that the Persian TRSC-C is a valid and reliable tool for measuring children symptoms. Availability of a valid and reliable checklist is a fundamental step in monitoring the symptoms of patients while receiving chemotherapy. © 2017, Shiraz University of Medical Sciences. All rights reserved.
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