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Myofibroblastoma of the Breast: A Morphologic and Immunohistochemical Study of Three Cases Publisher



Saffar H1 ; Motevalli D1 ; Seirfar N2 ; Ebrahimi M3 ; Kumar PV2 ; Kosari F3 ; Tabriz HM3 ; Naderi S4 ; Shekarkhar G2
Authors
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Authors Affiliations
  1. 1. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran
  3. 3. Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Medicine (MBBS), University of Central Lancashire, Preston, United Kingdom

Source: Iranian Journal of Pathology Published:2021


Abstract

Myofibroblastoma (MFB) of the breast is an uncommon entity of benign spindle neoplasms of the breast. This tumour possesses a broad spectrum of histomorphological patterns. Distinguishing of myofibroblastoma variants from malignant mimics of this benign neoplasm is essential for pathologists to avoid further invasive surgical procedures. In this article, we report the clinical, morphological, and immunohistochemical features of three cases, including two females and one male patient with mammary myofibroblastoma with emphasis on the histomorphological findings. As there is not yet enough information about MFB, more reports of MFB are still required to more clarify the pathogenesis and potential predisposing factors of this rare type of breast tumours. © 2021.