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Quantitative Polarimetry Mueller Matrix Decomposition Approach for Diagnosing Melanoma and Non-Melanoma Human Skin Cancer Publisher



Vahidnia A1 ; Madanipour K1 ; Abedini R2 ; Karimi R1, 3 ; Sanderson J3 ; Zare Z1 ; Parvin P1
Authors
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Authors Affiliations
  1. 1. Physics Department, Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran
  2. 2. Department of Dermatology, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, ON, Canada

Source: OSA Continuum Published:2021


Abstract

A simple and effective polarimetric technique is used to discriminate benign lesions from cancerous ones. This method is based on key polarimetric parameters of diattenuation, depolarization, and retardance. Several samples of human skin exhibiting three kinds of cancer as well as benign specimens are examined using a polarimetric technique and results are compared with pathology diagnosis. In this study polarimetric parameters are taken into account as a reliable diagnostic tool to distinguish the cancerous lesions precisely and non-invasively. © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.