The Current State of Artificial Intelligence in Healthcare: A Narrative Review of Opportunities and Challenges Publisher



Mehraeen E ; Attarian N ; Afra A ; Parsakian S ; Seyedalinaghi S ; Bondareva IL
Source: Shiraz E Medical Journal Published:2026

Abstract

Context: The use of artificial intelligence (AI) in healthcare presents exciting opportunities and significant challenges. The AI can improve the accuracy, efficiency, and personalization of treatment planning and patient care. However, it also raises concerns about data privacy, algorithmic bias, and the need for ethical frameworks to guide its development and responsible implementation. This article explores both the opportunities and challenges associated with the ongoing integration of AI into the healthcare landscape. Methods: In this narrative review article, to identify relevant articles, we searched databases such as PubMed, Google Scholar, and Web of Science utilizing specific search terms like Artificial Intelligence, AI, AI applications, AI in healthcare, AI applications in healthcare, opportunities, challenges, future, and future challenges in July 2024. Articles published between January 1, 2017, and June 31, 2024, focusing on the opportunities and challenges associated with AI implementation in healthcare, were reviewed. Articles without available full texts, lacking published data, duplicated articles, case series, case reports, and conference abstracts were excluded. Results: This investigation involved a comprehensive review of 18 relevant articles from diverse geographical regions, encompassing various medical specialties, predominantly comprising review studies alongside one original research article. We demonstrated that opportunities for AI in different fields of healthcare, including dentistry, ophthalmology, cardiology, urology, and radiology, are significant. The identified challenges included data provision challenges and privacy issues, as well as accountability and ethical issues, AI hallucinations, concerns related to relying on and trusting AI, AI management, and job/educational transformation. Conclusions: As AI continues to shape the future of healthcare, challenges will emerge necessitating novel solutions; yet, amidst these challenges, prospects for enhanced patient care and professional expertise remain promising. © 2025 Elsevier B.V., All rights reserved.