Tehran University of Medical Sciences

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Inflammatory Breast Cancer in a Very Young Genetically Susceptible Woman: Case Presentation in a Tumour Board Session, Discussion and Decision-Making Publisher



Alipour S1, 2 ; Bayani L3 ; Seifollahi A4
Authors
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Authors Affiliations
  1. 1. Breast Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Surgery, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Radiology, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pathology, Arash Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Breast Cancer Published:2020


Abstract

Background: Inflammatory breast cancer is a very aggressive type of breast cancer which invades skin lymphatics. The standard treatment includes neoadjuvant chemotherapy followed by modified radical mastectomy and post-surgical radiation. Preserving the skin or nipple are not considered reasonable due to the involvement of the dermal lymphatics and therefore skin sparing or nipple-sparing mastectomy are not usually carried out for this type of breast cancer. Case presentation: In this article, we present a case of inflammatory breast cancer in a very young woman who was positive for BRCA2 genes. Question: The possibility to perform nipple sparing or skin sparing mastectomy and immediate breast reconstruction, and the indication for prophylactic contralateral mastectomy as discussed in the tumor board are presented in this article. Conclusion: Neither of the more conservative techniques of mastectomy was appropriate for this case. Also, the prognosis of the patient mostly depends on the course of the ipsilateral tumor and prophylactic mastectomy would be wise only if the subsequent course of the disease is favourable. © 2020 Farname Scientific Publishing Inc.