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Adrenocortical Carcinoma With Renal Vein Thrombus Extended to Inferior Vena Cava: A Case Report Publisher



Ayati M1 ; Shahbazi J1 ; Tehranchi A2 ; Ayati E1 ; Rezaei Y3
Authors
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Authors Affiliations
  1. 1. Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Urmia Urology and Nephrology Research Center, Urmia University of Medical Sciences, Urmia, Iran
  3. 3. Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, 5718749441, Iran

Source: International Surgery Published:2015


Abstract

Adrenocortical carcinoma (ACC) is a rare aggressive tumor. Renal vein and inferior vena cava (IVC) thrombi have been found as uncommon presentations of ACC; however, the implementation of comprehensive therapy has remained controversial in such cases. We report a case of a 46-year-old woman with a large ACC associated with the invasion of tumor to IVC confirmed by imaging and immunohistochemistry examinations. The patient was treated successfully using aggressive surgery, including adrenalectomy and thrombectomy adjunct to an adrenocorticolytic agent. However, she died of metastasis complications at 3-month follow-up period. ACC is a rare malignancy, mostly presenting in advanced stages with poor prognosis. Implementing aggressive surgical therapy might be effective for the management of such cases; however, the short survival duration in our case underscores the need for defining the precise therapy of metastatic ACC associated with venous invasion. © International College of Surgeons. All rights reserved.