Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Balo's Concentric Sclerosis: An Update and Comprehensive Literature Review Publisher Pubmed



Amini Harandi A1 ; Esfandani A1 ; Pakdaman H1 ; Abbasi M1 ; Sahraian MA2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Brain Mapping Research Center, Shahid Beheshti University of Medical Sciences, Tehran, 1333635445, Iran
  2. 2. MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, 1136746911, Iran

Source: Reviews in the Neurosciences Published:2018


Abstract

Balo's concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg's variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS. Treatment with intense immunosuppression may be indicated in patients with more aggressive form. New reports reveal more evidence regarding the pathophysiology and treatment strategies. © 2018 Walter de Gruyter GmbH, Berlin/Boston 2018.