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Prevalence of Human Herpesvirus-8 Among Hiv-Infected Patients, Intravenous Drug Users and the General Population in Iran Publisher Pubmed



Kakavandghalehnoei R1 ; Shoja Z2 ; Najafi A3 ; Mollahoseini MH4 ; Shahmahmoodi S1 ; Marashi SM1 ; Nejati A1 ; Jalilvand S1
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, 14155, Iran
  2. 2. Department of Virology, Pasteur Institute of Iran, Tehran, 1316943551, Iran
  3. 3. Department of Immunology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, 157856171, Iran
  4. 4. Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, 1983963113, Iran

Source: Sexual Health Published:2016


Abstract

Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P≤0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population. Journal compilation © CSIRO 2016.
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