Estimates of One, Three, and Five Year Survival Rate of Patients With Gastric Cancer in Iran Using the Meta-Analysis Method



Akhondzadeh E^{1, 3} ; Yavari P² ; Mehrabi Y^{1, 3} ; Kabir A⁴ Show Affiliations
Source: Iranian Journal of Epidemiology Published:2015

Abstract

Background and Objectives: Various studies have reported different survival rates of patients with gastric cancer in Iran, and there is no overall estimate of the survival rate. The aim of this study was to conduct a meta-analysis of one, three, and five-year survival rate of patients with gastric cancer in Iran. Methods: In this study, all of the national databases including Iran Medex, Magiran, SID, and Medlib and the English databases including Google Scholar and PubMed were searched by using the keywords “stomach cancer”, “survival rate” and other Persian and English synonymous keywords, in the period 1 392-1 339 . Then, all articles with inclusion criteria and acceptable quality were investigated. Der Simonian and Laird random effects models were used to combine the results of all studies. Other analyses including subgroup analysis, sensitivity analysis, and assessment of publication bias were performed by using the funnel plot, and Beg’s and Egger’s tests. Finally, the data was analyzed using STATA software. Results: Of the 235 articles found in the initial search, nine studies were eligible for this study. According to these studies, one, three and five-years survival rate of patients with gastric cancer was 0.57 (95% CI: 0.45-0.70), 0.29 (95% CI: 0.22-0.37), 0.17 (95% CI: 0.13-0.21), respectively. Conclusion: Researches conducted in different parts of Iran are limited and there are no exact statistics on the survival rate in other parts of Iran. Therefore, further studies in the whole country are required to obtain more precise estimates of the survival and factors affecting it. © 2015, Iranian Epidemiological Association. All rights reserved.