Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol

Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol Publisher

Saadatjoo N¹ ; Javaheri M^{1, 2} ; Saemian N² ; Amini M³

Show Affiliations

1. Department of Organic Chemistry, Faculty of Chemistry, Semnan University, P.O. Box 35131-19111, Semnan, Iran
2. Applied Radiations Research School, Nuclear Science and Technology Research Institute, P.O. Box 11365-3486, Tehran, Iran
3. Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, 14176, Iran

Source: Radiochemistry Published:2016

Abstract

2-[2-(4-(Dibenzo[b, f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy]ethanol (Quetiapine) labeled with 14C in 11-position was synthesized in five steps from [carboxy-14C]anthranilic acid. The key precursor of the target product is [11-14C]dibenzothiazepin-11(10H)-one. The reaction is performed as one-pot process. © 2016, Pleiades Publishing, Inc.

Style	Citing Format
MLA	Saadatjoo N, et al.. "Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol." Radiochemistry, vol. 58, no. 5, 2016, pp. 528-531.
APA	Saadatjoo N, Javaheri M, Saemian N, Amini M (2016). Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol. Radiochemistry, 58(5), 528-531.
Chicago	Saadatjoo N, Javaheri M, Saemian N, Amini M. "Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol." Radiochemistry 58, no. 5 (2016): 528-531.
Harvard	Saadatjoo N et al. (2016) 'Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol', Radiochemistry, 58(5), pp. 528-531.
Vancouver	Saadatjoo N, Javaheri M, Saemian N, Amini M. Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol. Radiochemistry. 2016;58(5):528-531.
BibTex	@article{ author = {Saadatjoo N and Javaheri M and Saemian N and Amini M}, title = {Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol}, journal = {Radiochemistry}, volume = {58}, number = {5}, pages = {528-531}, year = {2016} }
RIS	TY - JOUR AU - Saadatjoo N AU - Javaheri M AU - Saemian N AU - Amini M TI - Preparation of a Carbon-14 Analog of 2-[2-(4-(Dibenzo[B, F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy]Ethanol JO - Radiochemistry VL - 58 IS - 5 SP - 528 EP - 531 PY - 2016 ER -

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