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Successful Treatment of Pulmonary Embolism Causing Cardiac Arrests With Reteplase During Neurosurgery: A Case Report Publisher



Yousefimazhin E1 ; Mojtahedzadeh M1 ; Karballaeimirzahosseini H1 ; Hassanpour R1 ; Sharifnia H2 ; Najmeddin F1 ; Ameli A2 ; Khademabbasi MJ2 ; Fotouhi M1 ; Etezadi F2 ; Khajavi MR2 ; Moharari RS2 ; Pourfakhr P3 ; Ahmadi A2 Show All Authors
Authors
  1. Yousefimazhin E1
  2. Mojtahedzadeh M1
  3. Karballaeimirzahosseini H1
  4. Hassanpour R1
  5. Sharifnia H2
  6. Najmeddin F1
  7. Ameli A2
  8. Khademabbasi MJ2
  9. Fotouhi M1
  10. Etezadi F2
  11. Khajavi MR2
  12. Moharari RS2
  13. Pourfakhr P3
  14. Ahmadi A2
  15. Neishaboury MR2
  16. Najafi A3
Show Affiliations
Authors Affiliations
  1. 1. Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Anesthesiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Anesthesia, Critical Care, and Pain Management Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Anesthesiology and Critical Care Published:2024


Abstract

Pulmonary embolism can cause cardiac arrest. Fibrinolytic therapy and surgical embolectomy can be used to manage it. This case report presents the clinical course of a patient who experienced intraoperative cardiac arrest resulting from massive pulmonary embolism. The patient encountered three instances of cardiac arrest requiring 35 minutes of cardiopulmonary resuscitation. Subsequent treatment involved the administration of reteplase, a thrombolytic agent. Following resuscitation, the patient developed multiple organ dysfunction in the intensive care unit, necessitating the use of diverse medications. Successful resolution of organ dysfunction led to the patient's transfer to the neurosurgery department. This case highlights the complexities involved in managing pulmonary embolism-induced cardiac arrest and subsequent multiorgan dysfunction, emphasizing the significance of a multidisciplinary approach in the comprehensive care and treatment of these patients. © 2024 Tehran University of Medical Sciences.