Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach

Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach Publisher Pubmed

Zamani R^{1, 2} ; Shahkarami S^{3, 4} ; Rezaei N^{4, 5, 6}

Source: Allergologia et Immunopathologia Published:2021

Abstract

Primary immunodeficiency diseases (PIDs) are a group of more than 400 disorders representing aberrant functioning or development of immune system. Hypopigmentation syndromes also characterize a distinguished cluster of diseases. However, hypopigmentation may also signify a feature of genetic diseases associated with immunodeficiency, such as Chediak-Higashi syndrome, Griscelli syndrome type 2, Hermansky-Pudlak syndrome type 2 and type 10, Vici syndrome, and P14/LAMTOR2 deficiency, all of which are linked with dysfunction in vesic-ular/endosomal trafficking. Regarding the highly overlapping features, these disorders need a comprehensive examination for prompt diagnosis and effective management. As an aid to clinician, distinguishing the pathophysiology, clinical phenotype, and diagnosis as well as treatment options of the six mentioned PID disorders associated with hypopigmentation are described and discussed in this review. © 2021. Codon Publications. Published by Codon Publications. All Rights Reserved.

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Nima Rezaei (7)

Amir Ali Hamidieh (4)

Style	Citing Format
MLA	Zamani R, Shahkarami S, Rezaei N. "Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach." Allergologia et Immunopathologia, vol. 49, no. 2, 2021, pp. 178-190.
APA	Zamani R, Shahkarami S, Rezaei N (2021). Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach. Allergologia et Immunopathologia, 49(2), 178-190.
Chicago	Zamani R, Shahkarami S, Rezaei N. "Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach." Allergologia et Immunopathologia 49, no. 2 (2021): 178-190.
Harvard	Zamani R, Shahkarami S, Rezaei N (2021) 'Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach', Allergologia et Immunopathologia, 49(2), pp. 178-190.
Vancouver	Zamani R, Shahkarami S, Rezaei N. Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach. Allergologia et Immunopathologia. 2021;49(2):178-190.
BibTex	@article{ author = {Zamani R and Shahkarami S and Rezaei N}, title = {Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach}, journal = {Allergologia et Immunopathologia}, volume = {49}, number = {2}, pages = {178-190}, year = {2021} }
RIS	TY - JOUR AU - Zamani R AU - Shahkarami S AU - Rezaei N TI - Primary Immunodeficiency Associated With Hypopigmentation: A Differential Diagnosis Approach JO - Allergologia et Immunopathologia VL - 49 IS - 2 SP - 178 EP - 190 PY - 2021 ER -

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