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Advances in Preclinical Pet Instrumentation Publisher Pubmed



Amirrashedi M1, 2 ; Zaidi H3, 4, 5, 6 ; Ay MR1, 2
Authors
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Authors Affiliations
  1. 1. Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, CH-1211, Switzerland
  4. 4. Geneva University Neurocenter, Geneva University, Geneva, CH-1205, Switzerland
  5. 5. Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, 9700, RB, Netherlands
  6. 6. Department of Nuclear Medicine, University of Southern Denmark, Odense, 500, Denmark

Source: PET Clinics Published:2020


Abstract

In the light of ever-increasing demands for PET scanner with better resolvability, higher sensitivity and wide accessibility for noninvasive screening of small structures and physiological processes in laboratory rodents, several dedicated PET scanners were developed and evaluated. Understanding conceptual design constraints pros and cons of different configurations and impact of the major components will be helpful to further establish the crucial role of these miniaturized systems in a broad spectrum of modern research. Hence, a comprehensive review of preclinical PET scanners developed till early 2020 with particular emphasis on innovations in instrumentation and geometrical designs is provided. © 2020 Elsevier Inc.