Advances in Preclinical Pet Instrumentation Publisher Pubmed

Summary: How can PET scanners be made better? A review reveals advances in miniaturized systems for noninvasive rodent research—key for future studies! #PETScanners #ResearchTech

Amirrashedi M^{1, 2} ; Zaidi H^{3, 4, 5, 6} ; Ay MR^{1, 2}
Source: PET Clinics Published:2020

Abstract

In the light of ever-increasing demands for PET scanner with better resolvability, higher sensitivity and wide accessibility for noninvasive screening of small structures and physiological processes in laboratory rodents, several dedicated PET scanners were developed and evaluated. Understanding conceptual design constraints pros and cons of different configurations and impact of the major components will be helpful to further establish the crucial role of these miniaturized systems in a broad spectrum of modern research. Hence, a comprehensive review of preclinical PET scanners developed till early 2020 with particular emphasis on innovations in instrumentation and geometrical designs is provided. © 2020 Elsevier Inc.