Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones

Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones Publisher

Mohammadhosseini N¹ ; Moradi S¹ ; Khoobi M² ; Shafiee A²

Show Affiliations

1. Faculty of Chemistry, Tehran-North Branch, Islamic Azad University, Tehran, Iran
2. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Heterocyclic Chemistry Published:2016

Abstract

Novel 6-mercapto-12-phenethyl-quinazolino[3,4-a]quinazolinone derivatives were synthesized through a user-friendly five-step reaction starting from isatoic anhydride. All products were characterized by IR, 1H-NMR, 13C-NMR spectroscopy, and chemical analysis. All of them were evaluated for their in vitro cytotoxic activity against two cell lines namely MOLT-4 (human lymphoblastic leukemia) and MCF-7 (human breast adenocarcinoma). © 2015 HeteroCorporation

Style	Citing Format
MLA	Mohammadhosseini N, et al.. "Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones." Journal of Heterocyclic Chemistry, vol. 53, no. 5, 2016, pp. 1595-1602.
APA	Mohammadhosseini N, Moradi S, Khoobi M, Shafiee A (2016). Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones. Journal of Heterocyclic Chemistry, 53(5), 1595-1602.
Chicago	Mohammadhosseini N, Moradi S, Khoobi M, Shafiee A. "Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones." Journal of Heterocyclic Chemistry 53, no. 5 (2016): 1595-1602.
Harvard	Mohammadhosseini N et al. (2016) 'Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones', Journal of Heterocyclic Chemistry, 53(5), pp. 1595-1602.
Vancouver	Mohammadhosseini N, Moradi S, Khoobi M, Shafiee A. Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones. Journal of Heterocyclic Chemistry. 2016;53(5):1595-1602.
BibTex	@article{ author = {Mohammadhosseini N and Moradi S and Khoobi M and Shafiee A}, title = {Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones}, journal = {Journal of Heterocyclic Chemistry}, volume = {53}, number = {5}, pages = {1595-1602}, year = {2016} }
RIS	TY - JOUR AU - Mohammadhosseini N AU - Moradi S AU - Khoobi M AU - Shafiee A TI - Synthesis of Novel 6-Mercapto-12-Phenethyl-Quinazolino[3,4-A]Quinazolinones JO - Journal of Heterocyclic Chemistry VL - 53 IS - 5 SP - 1595 EP - 1602 PY - 2016 ER -

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