Tehran University of Medical Sciences

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Photo/Electro-Mediated Radical Cascade Functionalization/Cyclization Reactions Involving N-Acryloyl 2-Aryl Indoles/Benzimidazoles Publisher



Doraghi F ; Abbasi A ; Zomorodiyan N ; Kermaninia S ; Dostkoh RH ; Larijani B ; Mahdavic M
Authors

Source: RSC Advances Published:2025


Abstract

Indolo/benzimidazo-isoquinoline scaffolds are frequently found in many natural products, pharmaceuticals, and organic materials. Owing to their prominent properties, in recent years, numerous studies have been performed on the synthesis of indolo/benzimidazo-isoquinoline derivatives via photo-, and electro-promoted functionalization/cyclization reactions of N-acryloyl 2-aryl indoles/benzimidazoles. In this review, we describe these fascinating transformations and discuss their mechanistic insights. © 2025 Elsevier B.V., All rights reserved.