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A Case of Severe Generalized Granuloma Annulare Responding Well to Tofacitinib Publisher



Alzahawi S1 ; Ghandi N1, 2 ; Azhari V3 ; Balighi K1, 2
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Case Reports in Dermatological Medicine Published:2025


Abstract

Granuloma annulare is a noninfectious, granulomatous skin disorder that typically presents as symmetrical, asymptomatic, annular, or arciform plaques with slightly raised edges, often found on the back of the hands or feet. This report highlights the successful use of tofacitinib in treating resistant/generalized granuloma annulare in a 66-year-old male with a known history of hepatitis B, demonstrating its potential as an effective therapeutic option. Copyright © 2025 Saman Al-Zahawi et al. Case Reports in Dermatological Medicine published by John Wiley & Sons Ltd.
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