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Ovarian Mature Cystic Teratoma With Malignant Transformation: Two Case Reports Publisher Pubmed



Tehranian A1, 2 ; Ghahghaeinezamabadi A1 ; Seifollahi A3 ; Kasraei S1 ; Dehghaninejad H1 ; Malekihajiagha A2
Authors
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Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, Arash Women’s Hospital, Tehran University of Medical Sciences, Rashid Ave, Resalat Highway, Tehranpars, P.O Box: 1653915981, Tehran, Iran
  2. 2. Research Development Center, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Pathology Department, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Medical Case Reports Published:2021


Abstract

Background: Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. Case presentation: We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis. Conclusion: The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival. © 2021, The Author(s).