18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study

18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study Publisher

Emamiardekani A¹ ; Harsini S^{1, 2} ; Fardesfahani A¹ ; Baseri F¹ ; Eftekhari M¹

Show Affiliations

1. Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Association of Nuclear Medicine and Molecular Imaging (ANMMI), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Iranian Journal of Nuclear Medicine Published:2019

Abstract

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare congenital disorder of mitochondrial DNA, presenting a wide range of clinical symptoms comprising headaches, seizures, aphasia, hearing loss, visual defects, and hemiparesis. Herein we report a case of a previously asymptomatic 40-year-old male who presented with recurrent headache, seizures, Wernicke’s aphasia, and impaired visual acuity. Investigations included CT, MRI, MR venography, MR spectroscopy, and PET/CT with 18F-fluorodeoxyglucose (18F-FDG-PET) of the brain. PET imaging showed diffuse increased 18F-FDG uptake in the right hemisphere and left temporal lobe; additionally, decreased 18F-FDG uptake was observed in the left frontoparietal lobe. The patient underwent treatment by levetiracetam, co-enzyme Q10, riboflavin, L-carnitine, and lacosamide, followed by improvement of his clinical signs and symptoms indicative of partial response to the therapy. © 2019 Tehran University of Medical Sciences. All rights reserved.

Style	Citing Format
MLA	Emamiardekani A, et al.. "18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study." Iranian Journal of Nuclear Medicine, vol. 27, no. 1, 2019, pp. 57-59.
APA	Emamiardekani A, Harsini S, Fardesfahani A, Baseri F, Eftekhari M (2019). 18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study. Iranian Journal of Nuclear Medicine, 27(1), 57-59.
Chicago	Emamiardekani A, Harsini S, Fardesfahani A, Baseri F, Eftekhari M. "18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study." Iranian Journal of Nuclear Medicine 27, no. 1 (2019): 57-59.
Harvard	Emamiardekani A et al. (2019) '18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study', Iranian Journal of Nuclear Medicine, 27(1), pp. 57-59.
Vancouver	Emamiardekani A, Harsini S, Fardesfahani A, Baseri F, Eftekhari M. 18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study. Iranian Journal of Nuclear Medicine. 2019;27(1):57-59.
BibTex	@article{ author = {Emamiardekani A and Harsini S and Fardesfahani A and Baseri F and Eftekhari M}, title = {18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study}, journal = {Iranian Journal of Nuclear Medicine}, volume = {27}, number = {1}, pages = {57-59}, year = {2019} }
RIS	TY - JOUR AU - Emamiardekani A AU - Harsini S AU - Fardesfahani A AU - Baseri F AU - Eftekhari M TI - 18F-Fdg Pet/Ct Findings in a Possible Melas Syndrome: A Case Study JO - Iranian Journal of Nuclear Medicine VL - 27 IS - 1 SP - 57 EP - 59 PY - 2019 ER -

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