Cxl Under Special Conditions: Pediatrics, Pack Cxl, Pixl, and Conductive Keratoplasty Publisher



Mohammadpour M¹ ; Khorraminejad M² Show Affiliations
Source: Keratoconus: Optical and Surgical Management Published:2024

Abstract

Corneal crosslinking (CXL) has emerged as an effective treatment for halting the progression of keratoconus.1–3 While the standard Dresden protocol is well-established for corneal crosslinking in adults, there has been increasing research into the use of CXL for pediatric keratoconus and other special situations.4–10 This chapter reviews the evidence for accelerated CXL protocols in children, as well as novel applications of CXL technology for conductive keratoplasty, post-SMILE ectasia, and treatment of infectious keratitis (PACK-CXL). Key studies evaluating the safety and efficacy of these specialized CXL techniques are summarized. This chapter provides an overview of how collagen crosslinking is being adapted and utilized for a wider range of corneal conditions beyond traditional applications in adult keratoconus patients. Research continues to evolve in this exciting field. © 2025 selection and editorial matter, Mehrdad Mohammadpour and Masoud Khorrami-Nejad; individual chapters, the contributors.