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Skull Base Osteomyelitis: A Case Report of Garcin Syndrome Due to Mucormycosis in Covid Pandemic Publisher



Tabari A1 ; Farrokh F1 ; Zeinalizadeh M2 ; Nasirmohtaram S3 ; Tabari A1 ; Salehi M5 ; Pakdel F6 ; Salahshour F7 ; Saffar H8 ; Mirashrafi F1 ; Sadrehosseini SM1
Authors
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Authors Affiliations
  1. 1. Otorhinolaryngology Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Neurosurgery and Skull Base Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Otorhinolaryngology Research Center, Guilan University of Medical Sciences, Rasht, Iran
  4. 4. School of Medicine, Azad University of Medical Sciences, Mashhad, Iran
  5. 5. Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  8. 8. Anatomical and Clinical Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: IDCases Published:2023


Abstract

Garcin syndrome is characterized by progressive unilateral multiple cranial nerve palsy without the presence of intracranial hypertension. In this case, we present a patient who experienced lower cranial nerve (CN 9–12) involvement attributed to post-mucormycosis osteomyelitis of the skull base. The osteomyelitis resulting from mucormycosis led to the development of Garcin syndrome, which manifested as progressive paralysis of the cranial nerves. It is important to recognize this rare complication and consider it in the differential diagnosis when evaluating patients with lower cranial nerve palsy following mucormycosis-related skull base osteomyelitis. © 2023 The Authors
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