Therapeutic Potential of Emodin: A Mini-Review of Its Anti-Biofilm and Antimicrobial Effects Publisher Pubmed



Teymouri S¹ ; Pourhajibagher M² ; Bahador A^{1, 3} Show Affiliations
Source: Infectious Disorders - Drug Targets Published:2025

Abstract

The resistance of biofilms to antimicrobial agents presents numerous challenges. The formation of biofilms leads to enhanced resistance to adverse environmental conditions, as well as to antimicrobial agents. Natural compounds have been of interest as potential therapeutic agents. Emodin, a natural anthraquinone compound, has recently attracted attention for its potential as a broad-spectrum antimicrobial agent. This ability could potentially help combat biofilm-associated infections and enhance the effectiveness of antimicrobial therapies. This review was carried out to evaluate the effects of emodin on microbial biofilms, determine its effectiveness in inhibiting and reducing biofilm formation, eradicate biofilms, and examine its antimicrobial effects. Our study shows that the use of emodin as an additional therapeutic agent in combating microbial biofilms holds considerable promise. As researchers continue to investigate how emodin interacts with microbial biofilms, there is excitement about the potential applications of this natural compound in addressing biofilm-related issues. However, it is suggested to pay more attention to evaluating the effects of emodin on microbial biofilms in future studies © 2024 Bentham Science Publishers.