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Method for the Synthesis of Chromenopyrimidine-Fused Azoles by Copper-Catalyzed Intramolecular Hetero-Diels–Alder Reaction Publisher



Ghomi MK2 ; Alizadeh N1 ; Moazzam A2 ; Hosseini S3 ; Bahadorikhalili S4 ; Larijani B2 ; Mahdavi M2
Authors
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Authors Affiliations
  1. 1. School of Chemistry, College of Science, University of Tehran, P. O. Box, Tehran, 14155-6455, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Electronic Engineering, Universitat Rovira i Virgili, Tarragona, 43007, Spain

Source: Chemistry of Heterocyclic Compounds Published:2023


Abstract

[Figure not available: see fulltext.] One-pot efficient copper-catalyzed approach for the synthesis of tetracyclic chromeno[4',3':4,5]pyrimido[1,2-b]indazolone and chromeno[4,3-d]-[1,2,4]triazolo[4,3-a]pyrimidine derivatives as a class of pharmacologically interesting compounds through the intramolecular domino condensation–aza-Diels–Alder reaction of aminoazoles and o-propargylated salicylaldehydes under reflux conditions has been described. © 2023, Springer Science+Business Media, LLC, part of Springer Nature.