Preterm Birth Does Not Increase the Risk of Developmental Dysplasia of the Hip: A Systematic Review and Meta-Analysis Publisher Pubmed



Ghaseminejadraeini A¹ ; Shahbazi P¹ ; Roozbahani G¹ ; Sharafi A¹ ; Shafiei SH¹ ; Fallah Y¹ ; Baghdadi S²
Source: BMC Pediatrics Published:2023

Abstract

Background: The purpose of this systematic review was to appraise the literature on the association between preterm birth and developmental dysplasia of the hip (DDH). Methods: Medline, Embase, Scopus, and Web of Science databases were queried for all studies pertaining to DDH and preterm birth. Data were imported and analyzed in Revman5 and Comprehensive Meta-Analysis (CMA) for pooled prevalence estimation. Results: Fifteen studies were included in the final analysis. There were 759 newborns diagnosed with DDH in these studies. DDH was diagnosed in 2.0% [95%CI:1.1–3.5%] of the premature newborns. Pooled incidence rate of DDH was not statistically different between those groups (2.5%[0.9%-6.8%] vs. 0.7%[0.2%-2.5%] vs. 1.7%[0.6%-5.3%];Q = 2.363,p = 0.307). Conclusions: In this systematic review and meta-analysis, we did not find preterm birth to be a significant risk factor for DDH. Data suggests that female sex and breech presentation are associated with DDH in preterm infants, but the data is scarce in the literature. © 2023, The Author(s).