Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?

Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look? Publisher

Behdadnia A¹ ; Allameh SF² ; Gharabaghi MA³ ; Najafizadeh SR¹ ; Roudsari AT¹ ; Ghajar A^{1, 4} ; Ganji M^{1, 4} ; Afarideh M^{1, 4}

Show Affiliations

1. Lupus and Rheumatology department, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
2. Department of General Internal Medicine, Imam Khomeini Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Pulmonary Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Intractable and Rare Diseases Research Published:2016

Abstract

A 31-year old woman with persistent fever for 6 weeks and unresponsive to antibiotic therapy came for rheumatologic investigation. After computed tomography (CT) studies of her neck, thorax and abdomen revealed bilateral cervical, axillary and retroperitoneal lymph node enlargements, histopathologic evaluation of the resected nodes showed features of histiocytic necrotizing lymphadenopathy suggestive of Kikuchi-Fujimoto's lymphadenopathy. Kikuchi- Fujimoto Disease (KFD) involving the retroperitoneal nodes is extremely unusual and even more challenging to diagnose when there are no early signs of extranodal involvement or abdominopelvic pain. We present a case of systemic KFD involving the cervical, axillary and retroperitoneal lymph nodes and emphasize the clinical interest to properly differentiate between the benign condition of KFD that requires no more than minimal to low dosage steroid therapy and the potentially life-threatening lupus lymphadenitis that mandates intensive immunosuppressive treatment.

Related Docs

1. Kikuchi-Fujimoto Disease: A Case Report, Acta Medica Iranica (2015)

Style	Citing Format
MLA	Behdadnia A, et al.. "Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?." Intractable and Rare Diseases Research, vol. 5, no. 4, 2016, pp. 301-305.
APA	Behdadnia A, Allameh SF, Gharabaghi MA, Najafizadeh SR, Roudsari AT, Ghajar A, Ganji M, Afarideh M (2016). Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?. Intractable and Rare Diseases Research, 5(4), 301-305.
Chicago	Behdadnia A, Allameh SF, Gharabaghi MA, Najafizadeh SR, Roudsari AT, Ghajar A, Ganji M, Afarideh M. "Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?." Intractable and Rare Diseases Research 5, no. 4 (2016): 301-305.
Harvard	Behdadnia A et al. (2016) 'Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?', Intractable and Rare Diseases Research, 5(4), pp. 301-305.
Vancouver	Behdadnia A, Allameh SF, Gharabaghi MA, Najafizadeh SR, Roudsari AT, Ghajar A, et al.. Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?. Intractable and Rare Diseases Research. 2016;5(4):301-305.
BibTex	@article{ author = {Behdadnia A and Allameh SF and Gharabaghi MA and Najafizadeh SR and Roudsari AT and Ghajar A and Ganji M and Afarideh M}, title = {Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look?}, journal = {Intractable and Rare Diseases Research}, volume = {5}, number = {4}, pages = {301-305}, year = {2016} }
RIS	TY - JOUR AU - Behdadnia A AU - Allameh SF AU - Gharabaghi MA AU - Najafizadeh SR AU - Roudsari AT AU - Ghajar A AU - Ganji M AU - Afarideh M TI - Systemic Kikuchi-Fujimoto Disease Bordering Lupus Lymphadenitis: A Fresh Look? JO - Intractable and Rare Diseases Research VL - 5 IS - 4 SP - 301 EP - 305 PY - 2016 ER -

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