Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases

Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases Publisher Pubmed

Skalova A^{1, 2} ; Vanecek T² ; Martinek P² ; Weinreb I⁴ ; Stevens TM⁵ ; Simpson RHW⁶ ; Hyrcza M⁷ ; Rupp NJ⁸ ; Baneckova M^{1, 2} ; Slouka D¹⁰ ; Svoboda T¹¹ ; Metelkova A¹² ; Etebarian A¹³ ; Pavelka J^{2, 14} Show All Authors

Skalova A^{1, 2}
Vanecek T²
Martinek P²
Weinreb I⁴
Stevens TM⁵
Simpson RHW⁶
Hyrcza M⁷
Rupp NJ⁸
Baneckova M^{1, 2}
Slouka D¹⁰
Svoboda T¹¹
Metelkova A¹²
Etebarian A¹³
Pavelka J^{2, 14}
Potts SJ³
Christiansen J³
Steiner P^{1, 2}
Michal M^{1, 9}

Show Affiliations

1. Sikl's Department of Pathology, Medical Faculty of Charles University, Faculty Hospital, E. Benese 13, Plzen, 305 99, Czech Republic
2. Bioptic Laboratory Ltd, Molecular Pathology Laboratory, Czech Republic
3. Ignyta Inc., San Diego, CA, United States
4. Department of Pathology, University Health Network, Toronto, ON, Canada
5. Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States
6. Department of Anatomical Pathology, University of Calgary and Foothills Medical Centre, Calgary, AB, Canada
7. Department of Pathology and Molecular Medicine, St. Joseph's Healthcare and Hamilton Health Sciences, McMaster University, Vancouver, BC, Canada
8. Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland
9. Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Czech Republic
10. Department of Otorhinolaryngology, Oncological Clinic, Faculty of Medicine, Plzen, Czech Republic
11. Department of Oncology and Radiotherapy, Oncological Clinic, Faculty of Medicine, Plzen, Czech Republic
12. Department of Clinical Oncology, Oncological Clinic, Faculty of Medicine, Plzen, Czech Republic
13. Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
14. Faculty of Education, University of West Bohemia, Plzen, Czech Republic

Source: American Journal of Surgical Pathology Published:2018

Abstract

ETV6 gene abnormalities are well described in tumor pathology. Many fusion partners of ETV6 have been reported in a variety of epithelial, mesenchymal, and hematological malignancies. In salivary gland tumor pathology, however, the ETV6-NTRK3 translocation is specific for (mammary analog) secretory carcinoma, and has not been documented in any other salivary tumor type. The present study comprised a clinical, histologic, and molecular analysis of 10 cases of secretory carcinoma, with typical morphology and immunoprofile harboring a novel ETV6-RET translocation. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

Experts (# of related papers)

Farzad Yazdani Bioki (1)

Ata Garajei (1)

Style	Citing Format
MLA	Skalova A, et al.. "Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases." American Journal of Surgical Pathology, vol. 42, no. 2, 2018, pp. 234-246.
APA	Skalova A, Vanecek T, Martinek P, Weinreb I, Stevens TM, Simpson RHW, Hyrcza M, Rupp NJ, Baneckova M, Slouka D, Svoboda T, Metelkova A, Etebarian A, Pavelka J, Potts SJ, Christiansen J, Steiner P, Michal M (2018). Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases. American Journal of Surgical Pathology, 42(2), 234-246.
Chicago	Skalova A, Vanecek T, Martinek P, Weinreb I, Stevens TM, Simpson RHW, Hyrcza M, et al.. "Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases." American Journal of Surgical Pathology 42, no. 2 (2018): 234-246.
Harvard	Skalova A et al. (2018) 'Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases', American Journal of Surgical Pathology, 42(2), pp. 234-246.
Vancouver	Skalova A, Vanecek T, Martinek P, Weinreb I, Stevens TM, Simpson RHW, et al.. Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases. American Journal of Surgical Pathology. 2018;42(2):234-246.
BibTex	@article{ author = {Skalova A and Vanecek T and Martinek P and Weinreb I and Stevens TM and Simpson RHW and Hyrcza M and Rupp NJ and Baneckova M and Slouka D and Svoboda T and Metelkova A and Etebarian A and Pavelka J and Potts SJ and Christiansen J and Steiner P and Michal M}, title = {Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases}, journal = {American Journal of Surgical Pathology}, volume = {42}, number = {2}, pages = {234-246}, year = {2018} }
RIS	TY - JOUR AU - Skalova A AU - Vanecek T AU - Martinek P AU - Weinreb I AU - Stevens TM AU - Simpson RHW AU - Hyrcza M AU - Rupp NJ AU - Baneckova M AU - Slouka D AU - Svoboda T AU - Metelkova A AU - Etebarian A AU - Pavelka J AU - Potts SJ AU - Christiansen J AU - Steiner P AU - Michal M TI - Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel Etv6-Ret Translocation: Report of 10 Cases JO - American Journal of Surgical Pathology VL - 42 IS - 2 SP - 234 EP - 246 PY - 2018 ER -

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