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Economic Evaluation of Clinical Pharmacists’ Services Provided for Solid Organ Transplant Patients: A Systematic Review Publisher



Hosseini MS1 ; Hajimiri SH2 ; Dashtikhavidaki S3 ; Nasiritoosi M3 ; Kebriaeezadeh A2
Authors
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Authors Affiliations
  1. 1. Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Organ Transplantation Medicine Published:2024


Abstract

Objective: This systematic review evaluated the economic impact of clinical transplant pharmacists’ intervention for solid organ transplant patients. Methods: A PRISMA compliant search of the literature was conducted up to 31th March 2024 using PubMed, Cochrane and Embase databases to identify the original articles published on economic outcomes of transplant pharmacists’ services. The quality of each included study was assessed using the CHEERS, ROBINS-I, and RoB 2 checklists. Results: Nine studies were included, six of which performed cost-benefit analyses and three conducted cost-saving analyses. Findings indicated that clinical pharmacist interventions led to reduced health-care cost through mechanisms such as increased cost savings, cost avoidance, and reduction in hospital length of stay. The reported range of benefit to cost ratio is 2.39 to 4.16. Some studies also highlighted the important role of pharmacists in improving patient care and clinical outcomes. Most of the pharmacists’ interventions were detection and management of drug related problems and prevention of adverse drug events. Conclusion: Findings indicates that clinical transplant pharmacist interventions in various settings, from inpatient wards to specialty clinics, pharmacies and mHealth platforms, contribute positively to economic outcomes and clinical care quality in solid organ transplant patients. © (2024), (Iranian Society for Organ Transplantation). All rights reserved.